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Alprostadil is produced endogenously and causes vasodilation by means of a direct effect on vascular and ductus arteriosus (DA) smooth muscle, preventing or reversing the functional closure of the DA that occurs shortly after birth. This results in increased pulmonary or systemic blood flow in infants. In infants, it is used for palliative, not definitive, therapy to temporarily maintain the patency of the ductus arteriosus until corrective or palliative surgery can be performed in neonates who have congenital heart defects and who depend upon the patent ductus for survival. In adults, it is used for the treatment of erectile dysfunction due to neurogenic, vasculogenic, psychogenic, or mixed etiology.

Other names for this medication:
Alprostadil, Caverject, Edex, Vitaros,

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We extracted data on patient sex, age, primary diagnoses, and comorbidities that could potentially affect the prevalence of pulmonary embolism. Diabetic cardiomyopathy (DCM) is defined as structural and functional changes in the myocardium due to metabolic and cellular abnormalities induced by diabetes mellitus (DM). We profiled 16 SFT samples using whole-genome DNA microarrays and analyzed their expression profiles with publicly available profiles of 36 additional SFTs and 212 soft tissue sarcomas (STSs).

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Dual energy X-ray absorptiometry (DXA) measurements of hip and spine bone mineral density (BMD) have an important role in the evaluation of individuals at risk of osteoporosis, and in helping clinicians advise patients about the appropriate use of anti-fracture treatment. It was hypothesized that animals with electrolytic lesions to the MT would have attenuated paw licking behavior during the second phase of the formalin tests as compared to sham lesion controls. Ghrelin may be associated with the beta-cell hypofunction and first-phase insulin secretion defects in T2DM. Association of PNPLA3 SNP rs738409 with liver density in African Americans with type 2 diabetes mellitus. A multifaceted distraction intervention may reduce pain and discomfort in children 4-6 years of age receiving immunisation.

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For example, magnetic mixers and magnetic actuators have been proposed to help handling fluids at a small scale. Special consideration has to be given to the fragile paediatric cardiopulmonary status especially in the presence of airway foreign body. Therefore, Au-Fe(3)O(4) hybrid nanoparticles are viable additive for formulating sustained drug delivery systems based on glycolic acid grafted chitosan.

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A friend rang with the answer: a dramatic air-sea rescue was being mounted just off the west coast of the South Mainland where she lives. Skewing to the LFA-3 adhesion pathway by influenza infection of antigen-presenting cells. We have analyzed the expression of MK mRNA and protein during tooth development in mouse embryos and studied the regulation of MK expression and the biological effects of MK protein in organ cultures. We describe a 37-year-old man who developed progressive multifocal leukoencephalopathy in association with sarcoidosis. Staphylococci contaminating goat dairy plants are potential biofilm producers.

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Iliac vein thrombosis was induced in six pigs by means of an occlusion-balloon catheter and thrombin injection. The purpose of this retrospective cohort study was to evaluate fracture and breast cancer rates among patients treated with raloxifene or alendronate. Inherited epidermolysis bullosa (EB) is a heterogeneous group of genetic disorders that present with skin and, in some cases, mucosal fragility, predisposing patients to the development of blisters and/or erosions after minimal trauma or friction. Primary Biliary Cirrhosis with a normal Alkaline Phosphatase: a case report.

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Function follows form: ecological constraints on odor codes and olfactory percepts. Carcinogenicity of vinyl chloride in Sprague-Dawley rats after prenatal and postnatal exposure. Unique seasonal mortality curves were created for 28 metropolitan statistical areas across the United States, and the amplitude and timing of mortality peaks were determined. Luminescence of polyethylene glycol coated CdSeTe/ZnS and InP/ZnS nanoparticles in the presence of copper cations. Numerical method for designing approximate cloaks with arbitrary shapes.

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