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Dutas (Dutasteride)
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Dutasteride

Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal mediator that plays a role in the development and enlargement of the prostate gland. Dutas was approved by the FDA in 2001 for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men as monotherapy or in combination with the α-adrenergic antagonist tamsulosin to enhance the therapeutic response. Its clinical efficacy against benign prostate hyperplasia in male patients is comparable to that of finasteride, a specific type II 5α-reductase inhibitor. However, unlike finasteride, Dutas is not yet indicated for the treatment of androgenic alopecia although it was demonstrated to be effective in several randomized, double-blind, placebo-controlled trials in androgenetic alopecia.

Other names for this medication:
Dutasteride, Deetor, Duodart, Duprost, Dutagen, Dutas, Dutasterida, Dute, Veltride,

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Raising leader awareness regarding transformational leadership behaviors and developing strategies to increase the use of these behaviors may be helpful to enhance organizational performance. Differential expression and regulation by activin of the neurotrophins BDNF and NT4 during human and mouse ovarian development. Pheromonal male-induced diestrus and cyclicity in aging intact and young estrogenized female rats. Three patients are reported with a neurological disorder in which hypokinesia and rigidity were the most prominent clinical signs.

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Enantioconvergent biohydrolysis of racemic styrene oxide to R-phenyl-1, 2-ethanediol by a newly isolated filamentous fungus Aspergillus tubingensis TF1. These extrinsic nerve fibres may originate from both sympathetic and vagal sensory ganglia. Subclinical hypothyroidism and indices for metabolic syndrome in Japanese women: one-year follow-up study.

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Papillomas of the upper urinary tract may be multiple, developing either simultaneously or at various times. The genetic control of type 1 (Le(a), Le(b), Le(c) and Le(d)), type 2 (X, Y, I, and H), type 3 and type 4 ABH and related antigens in different animal and human tissues is analyzed, taking into account the properties of the glycosyltransferases which are involved in their synthesis and considering possible competition for common acceptor and donor substrates.

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A comprehensive literature search was performed in PubMed, Embase, Web of Science, and reference lists. Mutations of the tyrosines did not result in loss of protease activity or the CD peak. Cloning, nucleotide sequence, and taxonomic implications of the flagellin gene of Roseburia cecicola. Thus, we conclude that, where response to a complex object is required, both lines and corners are equally important components in the visual processing of distractor stimuli. Results of provirus detection in peripheral blood and lymphoid organs and plasma viral RNA loads showed that 10/14 vaccinated cats were fully protected for 48 weeks against infection with FIV(FC1) whereas 5/5 controls were persistently infected with FIV(FC1).

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Red jungle fowl (Gallus gallus) as a model for studying the molecular mechanism of seasonal reproduction. Genetic diversity and the mating system of a rare Mexican pinon, Pinus pinceana, and a comparison with Pinus maximartinezii (Pinaceae). There were, however, no major differences in the patterns of noncollagenous or collagenous proteins between the two groups of tissues. When amphotericin B was combined with terbinafine or itraconazole, no synergy or antagonism was noted with all isolates included in this investigation. However, fudosteine easily forms fragments even at a photon energy near the ionization threshold, indicating the instability of its molecular ion.

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The role of sexual selection and conflict in mediating among-population variation in mating strategies and sexually dimorphic traits in Sepsis punctum. Adequate sedation, pain control and hydration may prevent the progression of this life-threatening condition.

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Constitutive and induced changes in plant quality impact higher trophic levels, such as the development of parasitoids, in different ways. Furthermore, research on cognitive biases and fear conditioning in anxious children and adolescents has progressed as quite distinct lines of investigation. Evaluation of the anticancer effect of cisplatin and etoposide against nude mice transplanted urological malignant tumors We find strong correlation between tractography-based basal ganglia parcellation and anatomical data from previously reported invasive tracing studies in nonhuman primates. Currently, much of the policy focus around reducing health disparities has been geared toward improving access, coverage, quality, and the intensity of healthcare.

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However, longer follow-up times are needed to warrant final conclusions. The records of a vision screening performed in 2005 at 4 preschools by a tertiary referral medical center in Kaohsiung, Taiwan were reviewed. The comparison group got a standard care at its mental health center. Associations between HMW exposures and lymphoma were evaluated using pooled unconditional logistic regression analyses.

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Diagnosis of STEMI includes data on anginal pain and persistent ST-segment elavation. Synthesis of oxo-dihydrospiroindazole-based acetyl-CoA carboxylase (ACC) inhibitors is reported.

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Nicotine decreases the porosity of the rat liver sieve: a possible mechanism for hypercholesterolaemia. Insertion of a retrovirus upstream of the amylase gene is responsible for the alteration in tissue specificity. If they do not expose outstanding neuroendocrine activity, they develop without clearly visible symptoms.

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Here we show that manipulation of protein kinase A (PKA) or its downstream adhesion component paxillin can reactivate the locomotive machinery of endballs in vitro and facilitate axon growth after injury in vivo. With this network approach we show that the modes of two-dimensional arrays that are evanescently coupled in the lateral direction and injection coupled in the longitudinal direction can be expressed in terms of the eigenvalues of matrices separately representing the lateral and longitudinal coupling. Also, the normal heart experiences a larger change in regional curvedness during contraction than the diseased heart. Indeed, it has been shown that lymph collected from shocked but not sham-shocked animals causes endothelial cell death, neutrophil activation, and bone marrow (BM) colony growth suppression in vitro. In the case-control analysis, the HBV group had significantly higher serum adiponectin, but lower triglyceride (TG) and high-density lipoprotein cholesterol (HDL) levels than the control group.

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Relationship between dopamine D2 receptor occupancy, clinical response, and drug and monoamine metabolites levels in plasma and cerebrospinal fluid. Philadelphia chromosome-positive acute lymphoblastic leukemia with monosomy 7 successfully treated with intermediate- and high-dose ara-C The effect of increasing the inter-plane disparity is strongly influenced by other stimulus parameters. We found that pT classification was a significant prognostic indicator for OS and DFS whereas tumor diameter, performance status, and sex were ones for OS. Rosiglitazone markedly increased body weight but reduced food intake, improved glucose control, and attenuated hyperlipidemia and liver and kidney injury.

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Mucosal surfaces are colonized by a complex microbiota that provides beneficial functions under normal physiological conditions, but is capable of contributing to chronic inflammatory disease in susceptible individuals. Although recent literature has emphasized the inappropriateness of short-term sexual dysfunction therapy for couples with severe marital discord, few objective measures for successfully screening couples have previously been described. As a result, GSCA provides a valuable new addition to analyzing gene sets of interest, complementary to Gene Ontology and Gene Set Enrichment analyses. Further studies of glutamatergic agents and extinction in cocaine dependence should include consideration of procedural variables that could have a major impact on study outcomes. Behavior of prostate-specific antigen (PSA) in prostate tissue: correlation with prostatic acid phosphatase (PAP)

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A study of shaggy reveals spatial domains of expression of achaete-scute alleles on the thorax of Drosophila. 2106 A (1) and cyclo-(N-MeVal-N-MeAla) (2), have been produced by the endophytic fungus no. The technique is applicable to other nano-sized colored objects, e.g. Strikingly, Fgfr2 is expressed throughout the floor plate of the MHB region. A previously healthy, 18-month-old girl developed edema and erythema around her left eye 1 week after getting sand in that eye.

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This effect was dependent upon the presence of the mineralocorticoid receptor and serum- and glucocorticoid-regulated kinase 1 (SGK1). The monolayer character of vertically aligned graphene is verified by Raman and X-ray absorption spectroscopy. Five patients had a coxa vara, and delayed union occurred in 4 patients. These data provide the first evidence that membrane-initiated E2 stimulation is able to induce and to potentiate the genomic activation of PR expression in the VMN. The adipokine might contribute to the increased metabolic and cardiovascular risk of the disease.

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Ten-year stability and variability, drinking patterns, and impairment in community youth with diagnostic orphan status of alcohol dependence. Insulin with chondroitinase ABC treats the rat model of acute spinal cord injury.

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A search for circulating immune complexes was negative, and antibodies against M-type phospholipase A(2) receptor could not be detected. Trust is a critical focus for HIV/STI informatics interventions for young African Americans. It is classically measured, in the pharmaceutical field, using the diametral compression test. Despite the pivotal role of soil microorganisms in agro-ecosystems, we still have a limited understanding of the complex response of the soil microbiota to organic and mineral fertilization in the very long-term.

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The ephrins/Eph receptors system seems to be an emerging target for pain drug discovery, because it is involved in the pathophysiology of many types of pain. The static and dynamic aspects of nasal anatomy determine the characteristics of the air flow passing through the nose and the thermo-hygrometric and particulated conditioning of the inhaled air.

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Additionally, morphometric examination of the manubrium from 40 adult human skeletons was performed. C57B1 mice were given orally one, two , or three doses of ritinyl palmitate or retinoic acid on day 11, 12, 13, or 14 or pregnancy to determine 1) if it was possible to produce cleft palate at any time during palatal development of the mouse embryo, and 2) the maternal and fetal levels of vitamin A associated with the production of clefts. The results of D2 region sequencing confirmed Mycosphaerella sense lato (including Davidiella and Eruptio) as monophyletic.

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In transcriptionally active nuclei, complexes of TBP interact with the nuclear matrix, while in mature erythrocytes this interaction disappears. Eight hundred and forty-two strokes were recorded, 70 per cent in University Hospitals, 20 per cent in private hospitals and 10 per cent at home.

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R231857 alone showed some pharmacodynamic changes compared with placebo. tauri chromosomes do not arrange into discrete, compact bodies or any other higher level of order.

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Each surgical attempt brings about a quasi-inevitable recurrence. Characterizing the impact of renal impairment on the clinical pharmacology of biologics. Recent advances in image-guided radiotherapy for head and neck carcinoma. Hsp70 and antifibrillogenic peptides promote degradation and inhibit intracellular aggregation of amyloidogenic light chains. We made an attempt to bring out the differences between chip-based as well as tubular continuous flow systems.

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The most widely used serum HCC marker is alpha-fetoprotein (AFP), while PIVKA-II, glypican-3 (GP3) and Squamous Cell Carcinoma Antigen -1 (SCCA-1) have been proposed as new biomarkers. Data from this analysis reinforce the utility of proficiency programmes to ensure the quality of the results obtained by a particular laboratory, as well as the importance of the post-analytical phase on the overall quality. We sought for hypoxia and Hif in mouse kidneys with CsA-induced toxicity, assessed their time course, Hif-mediated responses and the impact of interventional Hif upregulation. Rose Questionnaire responses among black and white inpatients admitted for coronary heart disease: findings from the Birmingham-BHS Project. Our data suggest that the TLR4 gene polymorphisms are not associated with susceptibility to, and clinical expression of, GCA in Italian patients.

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Ambiguity remains in the models explaining the photoinduced dynamics in pentacene thin films as observed in pump-probe experiments. ProTaper Universal retreatment system files alone proved to be faster than the other experimental groups. Gel electrophoretic analysis under nonreducing conditions showed that T76 underwent the formation of disulfide-linked multimers in the absence of reducing agent while gp88 behaved as monomers, suggesting that glycosylation is required for gp88 molecules to attain an appropriate conformation.

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However the anatomical variations are very frequent regarding the origin or the number of branches. Adherence was defined as hand hygiene/disinfection at an opportunity for hand hygiene. ICRPfinder is a powerful tool for finding or creating specific DNA patterns in a given target coding sequence.

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Expression of N-acetylglucosaminyltransferase III in hepatic nodules generated by different models of rat liver carcinogenesis. Characterization of the Ld-restricted cytotoxic T-lymphocyte epitope in the mouse hepatitis virus nucleocapsid protein. The complex processes of the human immune system prove to be challenging to capture and illustrate without proper reference to the spatial distribution of immune-related organs and systems. Students were assigned to a control group or to one of three intervention groups: viewing a self-instruction videotape, viewing and critiquing a videotape of their interview, or both of these activities. We present a case presenting with symptoms strongly suggestive of globus pharyngis.

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Neither of these procedures solves the problem of measuring intergroup attitudes of majorities and minorities in interaction. Identification and quantification of total coumarins from Urtica dentata Hand and its roles in promoting immune tolerance via TLR4-mediated dendritic cell immaturation.

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Octadecanoic acid, 3-hydroxytetradecanoic acid as well as small quantities of 3-hydroxydodecanoic acid were also identified. Role of FDG-PET staging in selecting the optimum patient for hepatic resection of metastatic colorectal cancer. Involvement of protein kinase C in agonist-stimulated goldfish ovulation. Midkine (MK) is a retinoic acid response cytokine, mostly expressed in embryonic tissues. High prevalence of drug resistance amongst HIV-exposed and -infected children in a tuberculosis prevention trial.

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This paper describes the differential uptake of the smoking cessation programme by doctors and midwives. Descriptive and multivariate statistical techniques are used to analyze data collected from each group. Super-resolution imaging techniques critically rely on bright fluorescent probes such as organic dyes or fluorescent proteins.

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Extrapolation techniques using asymptotic behavior considerations provide estimates for the energy of the physical system. This technique of combined isotopic and blue dye ARM and findings must now be validated.

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Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer. Broadly, the sharpness index belongs to a family of functions known as image sharpness functions that are potentially usable for image enhancement and restoration. There were no significant differences in either the follicular phase or luteal phase hormonal profiles of estradiol and progesterone, but there was a significantly reduced pregnancy rate in those women with severe endometriosis.

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The presence of an autoantibody to one or more cancer-associated antigens may provide an important addition to the armamentarium available to the clinician to aid early detection of SCLC in high-risk individuals. Our results demonstrate that RNA from autopsy-derived tissue, even up to 24 hours of autolysis, can be used to identify biologically relevant expression pattern differences, thus serving as a practical source for gene expression experiments. The lack of improvement in respiratory health among people living along the bypassed main road probably reflects a minimal change in exposure due to distance of residence from the road. Amino acid conversions by coagulase-negative staphylococci in a rich medium: Assessment of inter- and intraspecies heterogeneity. Effects of pyrimidine nucleoside phosphorylase inhibitors on hepatic fluoropyrimidine elimination in the rat.

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A solid-phase extraction technique for sample clean-up coupled with a new LC procedure is reported for the assay of diltiazem in plasma. The etiology of the disease is not well-understood but the initial lesion is a disorganization of collagenous structures.

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The purpose of this study was to investigate the predictive value of LA pressure for AF recurrence after PVI. Selective deficits in verbal working memory associated with a known genetic etiology: the neuropsychological profile of duchenne muscular dystrophy. To determine the presence of a similar misfolded WT SOD1 conformer in sALS tissue, we screened homogenates from patients diagnosed with sALS, fALS, and non-ALS disease in an organotypic spinal cord slice culture assay.

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Three MAbs reacted with TMV but not with dissociated viral subunits and these recognized the same residue exchanges. These cells showed altered morphology and PMA independent cell growth, but were not tumorigenic, corresponding to pre-malignant cells.

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A Synchronous undifferentiated nasopharyngeal carcinoma and infiltrating ductal carcinoma of the breast successfully treated with induction chemotherapy followed by local control of both tumours: a case report. The purpose of this study was to make a prognostic model for regional relapse in head and neck cancer using clinical and CT parameters. exhibit pronounced diuretic effects supporting the ethnopharmacological use of this plant as diuretic. A new route to synthesis of Ag(2)O micro-/nanostructures, including a mixture of cubes, pyramids, triangular plates, pentagonal rods, and bars, has been developed by pulsed excimer laser ablation of bulk silver in water using polysorbate 80 as surfactant. Motor learning via physical practice results in long-term potentiation (LTP)-like plasticity processes, namely potentiation of M1 and a temporary occlusion of additional LTP-like plasticity.

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The acoustic pulse amplitudes exhibit a sub-linear ( proportional, variantI(3/4)) pressure dependence on the laser intensity I characteristic of subcritical electron-ion plasma and demonstrating the avalanche enhancement of two-photon ionization above the breakdown threshold until the appearance of the critical plasma. Duplicate diet analysis for energy, protein, zinc and copper with estimates of biochemical status for Zn and Cu were undertaken in twenty-one elderly long-stay inpatients (mean age 82 (range 63-89) years) consuming their customary hospital diet and in a stable medical condition. Carbohydrate-binding module-cyclodextrin glycosyltransferase fusion enables efficient synthesis of 2-O-d-glucopyranosyl-l-ascorbic acid with soluble starch as the glycosyl donor. A transendocardial delivery and intracardiac ultrasound irradiation treatment catheter. Megalin and cubilin are cooperating receptors essential to the proximal tubule endocytic uptake of proteins from the glomerular ultrafiltrate.

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The objectives of this study were to establish normative data and predictive equations for both ankle dorsi- and plantar-flexion strength from a population of healthy subjects (children and adults), to assess the reliability of the measurements and to study the feasibility of using a novel dynamometer on a group of patients with a neuromuscular disorder. Previous studies have shown that mean 24-h GH concentrations determine plasma IGF-I levels in patients with acromegaly. Patients with status migrainosus often need to be admitted due to the severity of their headaches. In presumed ACh- or GABA-containing interneurons of C-type a significant decrease of firing rate, increase of activations and decrease of firing inhibitions, typical for these units in control conscious rats were found.

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The academia of the nursing profession has made tremendous advances in developing conceptual hartam house falstone reviews frameworks of nursing. Sex development is a complex process orchestrated by numerous genes. Its well recognized association with numerous diseases plus the limitations of our usual diagnostic tests may occasionally cause difficulty.

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It is essential to understand the various celtium 10 mg contraindicaciones del factors affecting corrosion resistance of surgical instruments and how it can be minimised.This paper investigates the effect on corrosion resistance from the clinical washing decontamination (WD) process, specifically by studying the changes in surface roughness and Cr/Fe ratio. Target sentences were presented simultaneously with a speech masker, and the spectral overlap between the pair (and hence the energetic masking) was systematically varied. Most prominent organelles of the rod-shaped aflagellate gamete in the male are an elongate nucleus formed like a canoe, a parallel arranged vacuole-like structure with a peripheral network of cisternae, and mitochondria and lamellar bodies on both ends of the cell. Seven weeks after transferring the above cells, body-weight loss and occult blood were significantly reduced in the mice that had been fed with GBF. The expression of DMTF1 was decreased in bladder cancer tissues.

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Sacrococcygeal teratoma (SCT) is one of the most common tumors in newborns with a birth prevalence of up to 1 in 21,700 births. However, efforts should be made to enable clinicians and nursing staff to identify and to provide psychological support to individuals who experience low quality of life and high emotional distress. We have previously reported that the Ste20-like kinase SLK is expressed in muscle tissue and is required for cell motility. Overweight/obese diabetic persons usually have normal/low LDL-cholesterol but high C-reactive protein (CRP) mittlere schiene im baclofen high levels. Induced hypertension is currently recommended for treating suspected DCI, whereas hemodilution and hypervolemia are not.

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