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Topirol (Topiramate)
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Topiramate

Topirol is a prescription drug. It comes in four forms: immediate-release tablets, immediate-release sprinkle capsules, extended-release capsules, and extended-release sprinkle capsules. All forms are taken by mouth. Topirol oral tablet is available as the brand-name drug Topirol. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug. This drug may be taken in combination with other drugs to treat epilepsy.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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RT-PCR and Western analyses revealed a substantial upregulation of both iNOS mRNA and protein, beginning ca 4 h after irradiation and persisting for at least 20 h. The recent releases of whole-genome sequences of pepper (Capsicum annuum L.) allow us to perform a genome-wide identification and characterization of the WRKY family. The NSAID-induced kinetic changes were considerably greater for (99m)Tc-DTPA than for (99m)Tc-MAG3. However, there is evidence of a general tendency towards increasing uniformity in knowledge as a result of the medical school years.

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A local Xenon clearance technique was used to study the direct effect of tranexamic acid on local tumour blood flow. CalS1 contains 16 predicted transmembrane helices with the N-terminal region and a large central loop facing the cytoplasm.

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Carminati (2002) tested the PAH for Italian in a variety of intrasentential contexts. A Bayesian phylogenetic analysis of 36 Ipomoea species using sequence data from the internal transcribed spacer region was compared with classification schemes based on traditional methods and a previously published cpDNA restriction fragment length polymorphism (RFLP) study.

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Using marine and cow models, we studied methods to enhance and direct the immune response to polynucleotide vaccines. Endogenous variability is likely to be important in spread but has not been studied empirically. On the contrary, the expression of the above mediators was very low in prostate tissue from immunized BALB/c mice, showing significantly slight increments only for CXCL1 and IL4. Research progress of perovskite materials in photocatalysis- and photovoltaics-related energy conversion and environmental treatment.

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Smoking without nicotine delivery decreases withdrawal in 12-hour abstinent smokers. Six rounds of selection using TRAP display were performed in approximately 14 h, yielding macrocyclic peptides with nanomolar affinity to their target protein. LPS also potently induces Lcn2/Ngal expression in podocytes in culture and in glomeruli in vivo.

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Degradative plasmid TOL provided singlet oxygen resistance for Pseudomonas strains. Our results suggest that MYH9 does not confer increased susceptibility to schizophrenia in the Japanese population, although we could not exclude possible contributions of other genes on 22q to the pathogenesis of schizophrenia. Previous studies on several species of green algae revealed that this group exhibits at least two types of telomeric sequences, a presumably ancestral type shared with land plants (Arabidopsis type, TTTAGGG) and conserved in, for example, Ostreococcus and Chlorella species, and a novel type (Chlamydomonas type, TTTTAGGG) identified in Chlamydomonas reinhardtii.

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Subjects were exposed to 3 randomly presented delay intervals during each experimental session (15, 30 and 60 s). Thirty-six patients were evaluated and treated for posterior urethral valves. In one patient with chronic renal failure who had received hemodialysis for more than 10 years, the transseptal puncture was unsuccessful. Contractile properties of fast muscle preparations regenerating in slow muscle beds. Arterial allografts in treating aortic graft infections: something old, something new.

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intracellulare N-260 (virulent SmT colonial variant) into the hind footpad. Agar diffusion assays with these two purified metabolites from the tri5-overexpressing transformant T. Herein, we report a method to tether one fibril formation inhibitor to TTR by disulfide bond formation. Conversely, overexpression of a dominant negative mutant of TNF receptor-associated factor-6 blocked TNF-alpha-, but not NGF-induced NFkappaB activation.

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The microvasculature of rabbit ovarian follicles were investigated three-dimensionally with resin casting/SEM technique during ovulation and corpus luteum formation. Together, these results define a novel role for tyrosine phosphatases in the complex mechanism of NMDA receptor regulation. The patients had an altered overall topology compared to the controls, suggesting that epilepsy is primarily a disorder of the cerebral network organization. Liver resection is considered the best treatment for metastatic colorectal cancer.

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This article describes adverse drug reactions in children and young people, their causes, types, pathways and mechanisms. This peptide acts as a disulfide-shuffling reagent and can pass the outer membrane of E.

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GAA and GIC were powerful inhibitors of lipid peroxidation and exhibit pro- and antioxidant behavior, with less toxicity of GIC. These data are discussed with respect to mechanisms of radiation-induced, site-specific chromosome 2 rearrangement and their implications for leukaemogenic initiation.

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Manganese-DPDP as a hepatobiliary contrast agent in the magnetic resonance imaging of liver tumors. The remaining 36 patients had no N-site recurrence at median follow-up of 37 months. These findings are consistent with the possibility that secretion of PDGF by human endothelial cells may be regulated independently of B-chain expression. SN-38 and CPT were more cytotoxic than 9-AC and TPT, and CPT-11 was almost inactive toward HT-29 cells. 2/50, p less than 0.001), with reversible thallium defects noted more frequently (4/6 vs.

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All subjects went through one session of fixation measurement with stimulus presentation and one session without stimulus presentation. The monitoring data for the initial phase of the investigation show lead levels well within OSHA permissible exposure limits. Coronary CT angiography in emergency department patients with acute chest pain: triple rule-out protocol versus dedicated coronary CT angiography. Active infective endocarditis: Clinical characteristics and factors related to hospital mortality. Theoretical predictions of stereoselectivity based upon transition state modeling provided good agreement with experiment.

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In all nine cases, exposure to diethylstilbestrol was associated with a history of bleeding during the pregnancy or prior miscarriage. Lower FA, reflecting compromised fiber microstructure in the inferior cingulate bundle, which links frontal and medial temporal episodic memory systems, was associated with piecemeal copy strategy and poorer immediate recall in the alcoholics. Combination of a reduced dose of an intrathecal local anesthetic with a small dose of an opioid: a meta-analysis of randomized trials. Fixed Drug Eruption (FDE) has its own characteristics and may be associated with ingestion of a number of agents.

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Tripartite comparison of single-incision and conventional laparoscopy in cholecystectomy: A multicenter trial. The family practitioner as a consumer of research needs to become familiar with the technique of meta-analysis because it is appearing with increasing frequency in the medical literature. Peri-implantitis PISF contained higher collagenase-2 levels and activity than GCF from similar deep CP sites. An indirect fluorescent antibody (IFA) procedure was developed for the detection of Cryptosporidium sp.

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Comparisons of cancer risks in persons by sibling cancers and those by parental cancers are informative of elucidating the potential genetic modes in the etiology of the cancers. To study nutrient intake among pregnant Finnish women at increased risk of GDM due to obesity or a history of GDM.

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It is essential to determine which snack foods are most affective for appetite control. The mass spectrometer was run using selected reaction monitoring for six adducted peptides.

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Encoding peptide sequences with surface-enhanced Raman spectroscopic nanoparticles. The fact that Pityrosporum ovale plays a part in seborrhoeic dermatitis is well established but the mechanism of this relationship has not been established. In the DMH-dosed rats, O6-methylguanine was formed to a greater extent in the BNF-treated colon than in the controls at 1, 12 and 24 h, whilst N7-methylguanine levels were essentially the same in the induced and uninduced rats. These efflux pumps serve as defence mechanisms and determine bioavailability and CNS concentrations of many drugs. Rapid changes in magnetic resonance imaging of muscle during the treatment of juvenile dermatomyositis.

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Medical professionals should be trained in adequate encoding of information and in standardized communication procedures with regard to error-prone information. A number of candidate genes affecting seed mineral concentration are discussed. A separate section will cover the available information on their pathophysiology. Successful treatment of dissecting cellulitis with ciprofloxacin.

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The rate of drift of circadian phase was calculated using a series of MOs (total number of hours the MO drifted divided by the total number of days studied). Trophic cascades: linking ungulates to shrub-dependent birds and butterflies. Hollow Ball-in-Ball CoxFe3-xO4 Nanostructures: High-Performance Anode Materials for Lithium-Ion Battery. To evaluate clinical and cytological effects of pimecrolimus in topical corticosteroid-treated and resolved AD lesions. Metabolized medium from the X63-m-IL2 cell line as a supplement to enhance immune response during in vitro immunizations.

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PET-based tumor volumes are strongly affected by the choice of threshold level. Contractile and histochemical properties of soleus (a slow-twitch muscle) and extensor digitorum longus (EDL, a fast-twitch muscle) were studied in mature rats after 3 months of streptozotocin-induced diabetes. Oncogenesis and the clinical significance of K-ras in pancreatic adenocarcinoma. Every single topic had to be rated by marks from 1 (very relevant) to 5 (not relevant). Involvement of catecholaminergic neurones of the nucleus of the solitary tract (NTS) in blood pressure regulation.

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Behavioral and electrophysiological evidence of a right hemisphere bias for the influence of negative emotion on higher cognition. The aim of the present study was to determine the functional role of LR1 in the migration and invasion of the trophoblast cell line, JEG3 cells.

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Cross-neutralizing antibodies against cosmopolitan and Melanesian strains of human T cell leukemia/lymphotropic virus type I in sera from inhabitants of Africa and the Solomon Islands. To keep the leaves in the correct orientation they were placed as single layers between coarse rigid plastic gauze. Although the purity of mature DCs was relatively low IL-4/GM-CSF-treated monocytes (hereafter called Aotus spp. Abnormal expression of glycogen phosphorylase genes in regenerated muscle. Surface characteristics were analyzed with field emission scanning electron microscopy, energy dispersive spectroscopy, and confocal laser scanning microscopy.

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This technology may lead to increased safety of blood products and reduce the risk of further propagation of prion diseases. Characteristic morphological changes in damaged astrocytes were seen which were also identified in experiments with simulated global ischemia. Also, CD150, a receptor for MV was not expressed on the surface of the LCs. Concerning the biological responses differences were observed related to the site quality and the infection status.

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Event-related potential measures of the intending process: time course and related ERP components. Ten rats per group survived 4 hours after cardiopulmonary bypass or the sham operation for immediate postoperative determination of tumor necrosis factor alpha-expressing cells (immunohistochemistry) and cerebral tumor necrosis factor alpha mRNA levels (polymerase chain reaction). Twenty-one children between 36 and 86 months with no or nonfunctional language participated in the study. Our patient was successfully treated as evidenced by negative urine culture and lack of ongoing symptomatology. Radiotherapy fields generally included not only chest wall (or breast) but also axillary, supraclavicular, and internal mammary nodes.

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A synthetic vaccine protects humans against challenge with asexual blood stages of Plasmodium falciparum malaria. Infectious PEDV could be recovered, and the rescued virus displayed phenotypic properties identical to the parental virus. Eyes pre-treated with dexamethasone 6, 4, and 2 h before challenge showed a significant reduction in conjunctival edema assessed histologically and clinically 1 h after challenge. Health indicators include mortality rates and life expectancy, birth outcomes, risk of illness, patterns of deteriorating health, cardiovascular disease, body mass index, hypertension, and depression.

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The likelihood of the relationship reflecting either a causal effect of depression on cognitive decline, or a common cause, or both, should be estimated. C25-C33 n-alkanes with odd-to-even predominance were observed in most surface soils of the wetlands, suggesting the dominant contribution of terrestrial higher plants for the soil organic matter (SOM), and the ubiquitous presence of unresolved complex mixture indicated the presence of petroleum contamination. During the hospitalization, in spite of treatment (steroids - medium dose, anti-histamine drugs and external steroids therapy) a progression of skin changes and appearance of some new single changes were observed.

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Heparin is also able to partially protect HBGF-I from thermal denaturation as demonstrated by the ability of heparin to protect HBGF-I from trypsin digestion. The rate of increase in the number of falls and risk of falling was greater in people with AD.

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This work demonstrates that inclusion of hydroxyapatite nanoparticles within a cyclic acetal nanocomposite hydrogel may enhance BMSC differentiation by promoting endogenous osteogenic signal expression. While living donors provide anywhere from a small to a large fraction of kidneys for transplantation in different countries, at least one-third of these donors are incompatible with their potential recipients.

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Predation pressure acts on the behaviour and morphology of prey species. Changes in blood coagulation-related parameters in phenobarbital-treated rabbits. Experiments confirmed modest top-down control of algae, whereas fertilisation had no general effect.

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IL-10 produced a consistent but modest reduction in IL-1alpha-induced IL-6 mRNA levels (not IL-1beta or TNF-alpha), but this was not reflected by reduced IL-6 protein secretion. Beclomethasone dipropionate in a dose of 800 micrograms/day may suppress the hypothalamo-pituitary-adrenal axis if used for long periods (six months). Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions.

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They also preferred a previous lying site to a new one, often exclusively and independently of floor material. Supporting health care sector decisions using time-dependent endpoints (TDEs) such as time to progression (TTP), progression-free survival (PFS), and event-free survival (EFS) remains controversial. Stimulation of thromboxane/prostaglandin receptors (TP) attenuates endothelium-derived hyperpolarization (EDH).

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While absolute values of birthweights were lower than the WHO 2006 child growth standards there was a J shaped curve of birthweight and mortality. This may explain why isolated toxic doses of ethanol are rarely if ever associated with pancreatitis. : The VLBW children performed more poorly at age 5 yrs than did their counterparts.

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Such inactivation probably accounts for the increased incidence of gallbladder distention observed in premature neonates. This suggests that SKALP is covalently attached to epidermal proteins. Youth who are homeless and gay, lesbian or bisexual (GLB) are one of the most disenfranchised and marginalized groups in our society. To date, there are no clinical trials comparing pharmacogenetic acenocoumarol dosing algorithm versus routine clinical practice in VTE. Phi-square Lexical Competition Database (Phi-Lex): an online tool for quantifying auditory and visual lexical competition.

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The transcriptome of Echinostoma caproni adults: further characterization of the secretome and identification of new potential drug targets. The present study demonstrates that the onset and development of serotonergic (5-HT) projections to the Monodelphis olfactory bulb can be traced entirely after birth.

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The last few years have brought dramatic improvements for sample preparation and solubilization of protein for electrophoretic analyses. Antitumor activity and gene expression of polyplex micelles with various cross-linking rates were evaluated in mice bearing subcutaneously xenografted BxPC3 cell line, derived from human pancreatic adenocarcinoma, and polyplex micelles with optimal cross-linking rate achieved effective suppression of tumor growth. The antigen recognized by monoclonal antibody was identified by flow cytometry and radioimmunoassy, respectively. The flap is transected transversely, and half of the flap is used as an onlay to repair the urethra and the other half is used for additional skin coverage where needed on the penile shaft. The fit of alternative Children of Twin models were evaluated using the statistical program Mx.

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Concurrent calcium, phosphate and alkaline phosphatase were measured. The present study was conducted to elucidate the cumulative incidence and risk factors for lung cancer in IPF patients by retrospective longitudinal cohort analysis.

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Our findings suggest that even a modest smoking habit significantly increases the risk of death among Japanese men, and the risk of death diminishes soon after cessation of smoking. The chapter is divided in four big blocks, which treat the molecular biology concepts and techniques in relation to DNA, RNA, proteins and metabolites, respectively.

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Parsing neurobiological dysfunctions in obesity: nosologic and ethical consequences. Vocalizations from the participants were analyzed with a custom MATLAB program, and statistical analysis was conducted with SPSS software.

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Because of the size of its particle-a fiber-covered icosahedral protein capsid 0.75 microm in diameter-Mimivirus was initially mistaken for a parasitic bacterium. IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso. We report a very unusual case of a tall cell variant of papillary carcinoma arising in a thyroglossal duct cyst in association with a follicular variant of papillary microcarcinoma and a tall cell variant of papillary carcinoma arising from the thyroid gland. Latent variable modeling to analyze the effects of process parameters on the dissolution of paracetamol tablet.

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The fast phase was complete within a few seconds and was associated with the reduction of some of the disulfide bonds and with almost complete loss of the tertiary structure. Activation of MMP-1, MMP-2, MMP-3, and MMP-9 g ezol easyjet reviews induced by MIP-133 on human corneal epithelial and stromal cell cultures was examined by reverse transcriptase polymerase chain reaction (RT-PCR) and ELISA.

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The Kaplan-Meier method and the Cox-Mantel test were used to identify factors associated with mortality for univariate analysis and multivariate analysis, respectively. Actual allergic and pseudo-allergic reactions in dental practice The mean differences between initial and final MMO were 1.50 mm, being greatest at the 7 days evaluation and carbamazepine 200 mg er capsules lowest at 30 days, and were not statistically significant at any time. Sp1 activation of RNA polymerase II transcription complexes involves a heat-labile DNA-binding component.

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Gene expression levels of S100 protein family in blood cells are associated with insulin resistance and inflammation (Peripheral blood S100 mRNAs and metabolic syndrome). The two terms are strongly correlated with each other for the hydrogen-bonded pairs. A total of 171 patients treated with ursodeoxycholic acid were followed for as long as 20 years. An increase of SubG1 phase was combivir pep treatment effectiveness found in their cell cycle profiles, indicating apoptosis as the mode of cell death.

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It is supposed that divergence between vocal dapoxetine and sildenafil tablets used in diabetes repertoires of sister groups increases gradually over time due to random learning mistakes and innovations. At the receiving terminal, the encrypted image is reconstructed well via compressive sensing theory, and the original image can be decrypted with three reconstructed holograms and the correct keys. The ability of n-3 fatty acids to modify tissue factor pathway inhibitor (TFPI) and tissue plasminogen activator inhibitor (PAI-1) was also evaluated along with fibrinogen and thrombin-antithrombin III (TAT) complexes. Visceral fat is directly associated with liver inflammation and fibrosis independent of insulin resistance and hepatic steatosis.

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Diameters of the vessels and distances and relative position of the structures were recorded. To describe the results of revision rapivir y alcohol surgery for complications of trabeculectomy in a case series from an academic glaucoma service.

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Also, mating of the leg movements with the spacesuit shell was investigated The longest distance test elicited the fact of acquisition of stable motor skills in the unusual circumstances. Metiamide (10(-6) M), a specific H2 receptor antagonist, inhibited the responses to histamine and mysoline reviews on garcinia 4-MH in the guinea pig uterus and taenia coli. We have developed a software tool, AUTOGSCAN, that automates file formatting, the running of statistical analyses, and the summarizing of resulting statistics for whole genome scans with a push of a button, using several independent, and often idiosyncratic, statistical software packages such as MERLIN, SOLAR and GENEHUNTER.

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In addition to interacting with each biotine dama h&m coupon code other, the Tap53 and TaMdm2 proteins are also able to respectively bind human Mdm2 and p53, providing strong evidence for functional conservation. ACA are predictors for a favorable prognosis, while anti-topo I are correlated with a poor prognosis and SSc-related mortality. Here, we provide the first characterization of two full-length gp130 cytokine receptors from the cDNA of the red-legged salamander (Plethodon shermani).

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Colloidal osmotic state of the blood in surgical patients before an operation MicroRNA-34a (miR-34a) can function as a tumor suppressor in some cancers through negative regulation of gene expression. We report here that the synovium of transgenic arthritic mice expressing human tumour necrosis factor (TNF) contains numerous mast cells (MC) and that their appearance is a phenomenon which was correlated to the local increase cefobid renal dose adjustment in NGF level. Challenging stereotypes: sexual functioning of single adults with high functioning autism spectrum disorder.