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Induction of repair synthesis of DNA in mammary and urinary bladder epithelial cells by N-hydroxy derivatives of carcinogenic arylamines. The subjects in group F had the highest scores on both occasions on the Somatic Anxiety and Muscular Tension scales, although the subjects in group FI had the lowest scores. Chitinases are enzymes that digest chitin molecules, present principally in insects and fungi. The currently described models do not pose major improvements over previously described methods.

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Plasma concentrations of norepinephrine were related to the severity of the heart failure, plasma cyclic AMP concentrations, and pulmonary artery pressures. A novel approach, based on the use of cardiac biomarkers has emerged in the last decade, resulting in a cost-effective diagnostic tool for early, real-time identification, assessment and monitoring of cardiotoxicity.

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These findings may be associated with the enterohepatic recirculation. This paper examined the impact of leadership characteristics of nursing unit managers, as perceived by staff nurses, on staff satisfaction and retention. In the present study, the full-length cDNA sequence of turbot CXCR4 was obtained, and sequence analysis indicated that its primary structure was highly similar to CXCR4 from other vertebrates. Similarly, when anchoring the measures to a disease-specific questionnaire - Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) - both questionnaires could differentiate between WOMAC severity levels but the EQ-5D showed greater differences.

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The results are important for our understanding of the movement profiles of the masticatory system. Use of verapamil in the treatment of pain in acute myocardial infarction The cystic fibrosis gene, its product CFTR protein and its mutations Characterization of high affinity monoclonal antibodies against the luteinizing hormone-releasing hormone. The Cancer Genome Atlas (TCGA) project is a large-scale effort with the goal of identifying novel molecular aberrations in glioblastoma (GBM).

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Antiobesity effects of melanin-concentrating hormone receptor 1 (MCH-R1) antagonists. Prospective clinical trial comparing the effects of conventional Twin-block and mini-block appliances: Part 2. Evidence of a myco-heterotroph in the plant family Ericaceae that lacks mycorrhizal specificity. p53 alterations in human squamous cell carcinomas and carcinoma cell lines.

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Action potentials were recorded from rat retinal ganglion cell fibers in the presence of a uniform field, and the maintained discharge pattern was characterized. Determination of optimal treatment strategy becomes difficult for the orthopaedic surgeons and as a consequence, the patients suffer not only from therapeutic failure but also due to adverse side effects of antibiotics and financial loss due to additional stay at hospitals. Ventilation obstacles in the nose are frequent and varied: they are examined with the consequences of nasal obstruction at local and zonal level.

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The latter property was evaluated using the pairwise disconnectivity index, which we have recently introduced to quantify how critical network components are for the internal connectedness of a network. Recently, several reports have suggested that innervation influences wound healing. Given that there are currently a number of promising therapies under development that target SOD1, it is of critical importance to better understand the role of misfolded SOD1 in sALS. In this study, we present evidence that AMPAR recycling occurs through different pathways regulated by synaptic activity. Determination of vitamin E (tocopherol) in the blood serum of patients with drug-induced disease

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Treatment of cells with alpha-difluoromethylornithine (DFMO), which leads to the intracellular depletion of the polyamines putrescine and spermidine, is known to increase the cell killing induced by the DNA cross-linking chemotherapeutic agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU). Brief report: deficient thymic output in rheumatoid arthritis despite abundance of prethymic progenitors. The catB and catC genes encode cis,cis-muconate lactonizing enzyme I (EC 5.5.1.1) and muconolactone isomerase (EC 5.3.3.4), respectively.

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Other important breeding parameters such as the start of egg laying, the clutch size and the breeding success did not differ significantly among sites. Greater knowledge of the genetic and biochemical mechanisms underlying the germ-line modulation of lung tumor size in mice is relevant to other species, including humans, in that it may help identify new therapeutic targets in the fight against tumor progression. Activation rather than inactivation of the voltage-dependent sodium channel was strongly affected. Similarly, the ability of pharmacologic agents to modulate the post-cardiopulmonary bypass (CPB) inflammatory response has been previously elucidated in both the laboratory and clinical arena. Preparation and antibacterial activities of polyaniline/Cu0.05Zn0.95O nanocomposites.

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In the case of an articular-side tear, a transtendinous repair technique was used, whereas in the presence of a full-thickness tear, the tendon was refixated to the bone directly. Cytochromes P450 comprise a superfamily of proteins that play a crucial role in the biotransformation of numerous chemicals. Zero-inflated negative binomial regression and exploratory spatial analyses were employed.

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Our aims were to evaluate the utility of urinary L-FABP for the early detection of AKI and to examine whether podocyte injury is present in AKI patients using the biomarker of urinary PCX. Aged cancer patients had higher utilization rates than nonaged cancer patients throughout the year before a cancer diagnosis.

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Neural correlates of syntactic processing in the nonfluent variant of primary progressive aphasia. To treat the channel/membrane interface boundary conditions of the electric potential, an optimization approach is used to derive image charges by fitting the reaction-field potential expressed in terms of cylindric harmonics. Initially, glycopeptides are produced, the peptide portion of which consists of several amino acids, which are further hydrolyzed to yield a mixture of glyco-asparagines and oligosaccharide-alditols in the ratio of approximately 4:1. Although it is likely that PAH-HIV has an underlying etiology specifically related to HIV infection, it shares several key clinical and pathological similarities with other forms of PAH. Genetic deletion of sEH reduces vascular inflammation and edema and improves outcome after SAH.

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The interaction between environment and genetic traits under selection is the basis of evolution. To study the function(s) of the Rous sarcoma virus nucleic acid-binding protein p12, we constructed mutants by using two restriction sites in the p12 proviral coding sequence of the Prague C strain to insert KpnI synthetic linkers. A protein kinase C inhibitor, staurosporine, and an inhibitor of phospholipase A2, p-bromophen-acylbromide, inhibited stimulated PAF formation in both fractions.

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Greater ventral pallidal response to initial but not later PF during learning predicted higher behavioral WTP. A rhodopsin gene expressed in photoreceptor cell R7 of the Drosophila eye: homologies with other signal-transducing molecules. Experimental verification of the favorable activity of synthetic corticostimulin on brain edema induced by ischemia in rats

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Tetraploid cells were examined to determine if the chromosome bred true with respect to the three possible centromere configurations or if it could alternate between them. Allelic variants of the Plasmodium falciparum merozoite surface antigen 2 (MSA-2) in a geographically restricted area of Irian Jaya. Determination of sodium dioctylsulfosuccinate in dry beverage bases by liquid chromatography with post-column ion-pair extraction and absorbance detection. Medicinal plants are a rich source of biologically-active phytochemicals and have been used in traditional medicine for centuries. There is a need for more efficient RCT designs that accelerate development, minimize costs, and make trials more appealing to patients.

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This impairment in EGFR trafficking observed in cells depleted of ERM proteins is due to a delay in the recruitment of Rab7 on endosomes. This plethora of proteins and their varying evolutionary origin underlines the versatility of the IMC as a result of the adaption to a parasitic lifestyle. The results of this pilot study favor the continuing practice of blended learning environments as a viable option for course delivery in health care education. Long- and medium-chain triacylglycerols in neutral lipid-exchange processes with human plasma low-density lipoproteins.

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Drug protein binding in chronic renal failure: evaluation of nine drugs. For men, almost all indicators had a significant independent impact on risk of death. An underlying hypothesis for rapid cartilage loss in patients with osteoarthritis (OA) is that perturbation from normal joint mechanics produces locally high biomechanical strains that exceed the material properties of the tissue, leading to rapid destruction.

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HIV-central nervous system manifestations, here the AIDS-Dementia complex, are at the moment of special interest owing to its unexpected development. The purpose of this report is to demonstrate the severity of polyethylene wear by arthroscopy after total knee arthroplasty (TKA). Single-use thermoplastic microfluidic burst valves enabling on-chip reagent storage. More sophisticated methods of measuring the peripheral optical profile may be necessary to accurately compare the two modalities and to determine the true optical effect of the bifocal soft contact lens on the peripheral retina. Infertile women in Ghana have psychosocial health problems that are associated with their beliefs about infertility.

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The present study was carried out to analyze the sex differences in the retention of Cd in rats treated with a small amount of Cd, and its mechanisms. Comparison of genome-wide binding of MyoD in normal human myogenic cells and rhabdomyosarcomas identifies regional and local suppression of promyogenic transcription factors. Special attention will be dedicated to the increasing use of carbohydrates as molecular scaffolds for library synthesis. Prostate-specific antigen (PSA) isoform p2PSA in combination with total PSA and free PSA improves diagnostic accuracy in prostate cancer detection.

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Localized resectable neuroblastoma: results of the second study of the Italian Cooperative Group for Neuroblastoma. Fluorescein penetrates beyond the borders of the circumventricular organs into the surrounding neuropile. The behavioral polarity is not a function of the rate of locomotion of the particular stimulant used to orient the cells, but may reflect an asymmetric distribution of chemotactic receptors or the motile machinery.

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