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Sleep problems are associated with an increased risk of psychiatric and somatic diseases. Quantitatively modeling the equilibrium properties of thiol-decorated gold nanoparticles. Finally, we parameterized a simulation model linking data on fruit density and disperser abundance and behavior with empirical estimates of seed retention times to generate seed dispersal patterns in two hypothetical landscapes.

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To examine the associations between parent conversations about healthful eating and weight and adolescent disordered eating behaviors. Tracing thyroid hormone-disrupting compounds: database compilation and structure-activity evaluation for an effect-directed analysis of sediment.

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Norepinephrine stimulated spontaneous contractions in circular muscle and inhibited contractions in longitudinal muscle from mid-pregnancy until term. RNA probes, transcribed from synthetic DNA, for in situ hybridization.

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Numerous PGP-, VIP-, NPY, DBH- and TH- like immunoreactive (-LIR) nerves were associated with the smooth muscle bundles which comprised the intramural ureter. The results demonstrate that microbubble with US exposure could significantly enhance the reporter gene expression as compared with other groups. Achieving competencies in family medicine through continuing professional development.

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By conducting the injury severity study for MV and SV accidents involving trucks separately, some new or more comprehensive observations, which have not been covered in the existing studies can be made. Previous studies linked this exposure to an increased risk of respiratory illness, low birth weight (LBW) and other disorders. Recombinant blood clotting factor VIII is one of the most complex proteins for industrial manufacturing due to the low efficiency of its gene transcription, massive intracellular loss of its proprotein during post-translational processing, and the instability of the secreted protein. Protein feeding promoted a dramatic induction of the main regulatory gluconeogenic genes (glucose-6 phosphatase and phosphoenolpyruvate carboxykinase) in the kidney, but not in the liver. It is hoped that this study will help to inform the design of optimal gradient coils for split MRI systems with a large central gap.

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Glutamate dehydrogenase in astrocytes of the rat dentate gyrus following lesion of the entorhinal cortex. Recent advances in the treatment of intimate partner violence and abuse. 2000 ASHG Award for Excellence in Education: introductory speech for F. Primary fibroblasts isolated from human ACL specimens were treated with recombinant myostatin, and myostatin treatment increased fibroblast proliferation as well as the expression of tenascin C (TNC), type 1 collagen, and transforming growth factor-beta1.

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Therefore, the objective of this study was to evaluate the effects of chronic exposure to arsenic, estrogen, and their combination, on cell growth and transformation, and identify the mechanism behind these effects. The composition of the vaginal microbiota is an important health determinant. There is a long and controversial history of reports of immune activation associated with schizophrenia. The antibody failed to block the proliferation of primary T cells, or alloreactive T cell clones and blasts stimulated with HLA-specific monocytes or dendritic cells, even though IL-1 in the medium was neutralized.

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Quasi-elastic light scattering of Artemia ribosomes sedimented in a CsCl density gradient. The sensitivity of the method allowed detection of a least 50 pmoles of amino acid per mg of ganglioside with excellent reproducibility and little or no interference of by-products derived from hydrolysis of the glycosphingolipid. Patients admitted later than the second postburn day exhibited a significantly greater incidence of chondritis. Several examples from the studies at the Advanced Photon Source in Argonne National Laboratory are summarized, including excited-state metalloporphyrins, metal-to-ligand charge transfer (MLCT) states of transition metal complexes, and charge transfer states of metal complexes at the interface with semiconductor nanoparticles. Adaptor protein Nck1 binds a number of intracellular proteins and influences various signaling pathways.

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Fasting blood glucose, HbA(1C), plasma insulin and protein were estimated before and after the treatment, along with hepatic glycogen, and activities of hexokinase, glucose-6-phosphatase, fructose-1,6-bisphosphatase and glucose-6-phosphate dehydrogenase. Identification of a lens-specific regulatory region (LSR) of the murine alpha B-crystallin gene. We will discuss the advantages, special features, and limitations of the system. The mobility of residues C-terminal to Q62 is significantly greater than the equivalent residues of non-sequence-specific boxes, and these residues show a weaker association with the extended N-terminal segment than in non-sequence boxes. Small bowel intussusception: an unusual presentation of angioedema.

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Surgical design and simulation (SDS) is a useful tool to help surgeons visualize the anatomy of the patient and perform operative maneuvers on the computer before implementation in the operating room. Laparoscopic hemicolectomy with radical lymphadenectomy in such a patient was successfully performed by careful consideration of the mirror-image anatomy. In the Vibrio harveyi and Vibrio cholerae quorum-sensing circuits, multiple non-coding small regulatory RNAs called the quorum-regulated small RNAs (Qrr sRNAs) function to establish the global quorum-sensing gene expression pattern by modulating translation of multiple mRNAs encoding quorum-sensing regulatory factors. Brain dysmorphology in individuals with severe prenatal alcohol exposure.

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Group A received an intravitreal loading dose of bevacizumab (0.5 mg) on day 3, followed by five smaller injections (0.15 mg), one every third day. Although promising results have also been achieved with various combinations of drugs there is no conclusive evidence that chemotherapy improves survival, irrespective of whether it is given before (neoadjuvant or pre-emptive), with (concurrent) or after (adjuvant) local treatment. Anorganic bovine bone (ABB) graft has been extensively used as an osteoconductive material in the bone reconstructive surgeries. Supervisors differentiated between the curricula tracks in postgraduate year 3 (PGY-3), rating Standard Curriculum graduates higher than PBL graduates in 5 of 6 noncognitive items and in two of three general ratings.

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The commonality between chronic conditions that are treated with low-dose ketamine, such as specific chronic pain conditions, depression, and post-traumatic stress disorder, can be found in relation to the stress system, particularly the hypothalamus-pituitary-adrenal axis. Activation syndrome (AS) is a cluster of symptoms listed by the US Food and Drug Administration as possible suicidality precursors during antidepressant treatment. Symptomatic or asymptomatic patients with severe right ventricular dilatation due to pulmonary regurgitation may benefit from pulmonary valve replacement. Common bile duct obstruction during acute pancreatitis usually occurs in the early symptomatic phase of the illness, involves only the distal portion of the common bile duct, and subsides with clinical improvement. Young litter-mate pigs were kept at either 10 or 35 degrees C and fed either a high (H) or a low (L) food intake producing four groups: 10 H, 10 L, 35 H and 35 L.

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A comparison of the in vivo metabolism of phenothiazine and promazine in the neonatal guinea pig. Age-related changes of serum human atrial natriuretic polypeptide levels in normal subjects and clinical significance in liver cirrhosis, diabetes mellitus In addition, there are considerable differences in reported trends seemingly based on similar statistical methods and databases.

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The extent of cytoplasmic O-GlcNAc staining was graded as either low or high according to the intensity of the staining and the percentage of stained cells. Thus, a quantitative range of Hox-responsiveness was produced by slight sequence alterations that did not change HD binding sites of their relative spacing in the promoter.

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This study was performed to describe the clinical presentation, surgical outcome in patients with symptomatic myelopathy caused by ossification of the yellow ligament (OYL). Urine calcium and phosphorus increased, while urine oxalate fell. We then tested whether crabs preferred adult drills of either U. The thalamic reticular nucleus plays a crucial role in modifying the patterns of activity that can reach the cerebral cortex from the thalamus.

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Lipomatosis of the nerve, also known as fibrolipomatous hamartoma, is characterized by the infiltration of the nerve by fibro-fatty tissue. In contrast, many of the ambient gas concentrations were reasonable surrogates of personal PM2.5 exposures. Lung adenocarcinomas (LUADs) lead to the majority of deaths attributable to lung cancer.

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Detection of Echinococcus multilocularis infection in a colony of cynomolgus monkeys (Macaca fascicularis) using serology and ultrasonography. Improving glycaemic control and life skills in adolescents with type 1 diabetes: a randomised, controlled intervention study using the Guided Self-Determination-Young method in triads of adolescents, parents and health care providers integrated into routine paediatric outpatient clinics. Isolation, purification and identification of etiolation substrate from fresh-cut Chinese water-chestnut (Eleocharis tuberosa). Addition of the 13 genes, encoding initiator, DNA helicase, helicase loader, RNA primase and DNA polymerase III to the PURE system gave rise to a DNA replication system by a coupling manner. These findings will facilitate elucidation of the molecular mechanism and structural basis for rapid and direct heme transfer from Shp to HtsA.

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In Other Whites, age-adjusted mortality rates from lung cancer and from chronic obstructive pulmonary disease increased progressively in males and females. In these culture conditions, chondrocytes keep their phenotypic stability.

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Use of a Modified Canadian Occupational Performance Measure for Assistive Technology Outcomes in Postsecondary Education. The experimental values of Ki of native and immobilized aprotinin--enzyme complexes are equal to 0.037 and 0.045 nM for trypsin, 0.38 and 112.3 nM for pancreatic kallikrein and 34.4 and 454.5 nM for plasma kallikrein with N alpha-benzoyl-L-arginine ethyl ester as substrate, and to 82.6 and 231.7 nM for plasma kallikrein with a natural substrate--kininogen.

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Differences in rates of externalization from tumor cells in vitro and in the rates of washout from tumor and kidney in vivo were observed. The study demonstrated that administration of toluene at the dose used did not result in significant maternal toxicity. After 2 to 3 months in culture, this cell line secreted per day 18.9 micrograms albumin and 11.0 micrograms transferrin per 10(6) cells, 38.75 nmol total BA per mg cell protein, and up to 31 ng hGH per 10(6) cells without cloning hGH recombinant cells.

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Ultrastructural examination of white blood cells of 8 patients with neuronal ceroid lipofuscinosis showed the characteristic cytosomes, i.e. Thus, it is concluded that the amide I band for type III beta-turn structure appears in the range between 1,665 and 1,677 cm-1 and the amide III band between 1,265 and 1,286 cm-1. This included a 6-month chart review of cases with strongyloidiasis and randomly selected controls conducted to determine the association with immunocompromised states. Although as duodenal GIST was diagnosed, histologic examination for frozen sections during the procedure revealed tubular adenocarcinoma of the duodenum and pancreaticoduodenal lymph node metastasis of neuroendocrine carcinoma. Therefore, generalized ordered Probit models were estimated, and an indicator of health, net of cross-cultural effects was constructed for each respondent.

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Evaluation of an integrated orbital tissue expander in congenital anophthalmos: report of preliminary clinical experience. PCC 7120, provides evidence that calcium ions regulate heterocyst differentiation. GSH levels in these ascites tumors declined significantly without L-BSO treatment as the tumor rapidly grew in the IP space. Orthodontic tooth movement of upper first molars was performed in twelve aged (500 days old) rats.

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Experts have called for a comprehensive didactic curriculum in orthopaedic residency training. The antioxidant function of 2-Cys peroxiredoxin (Prx) involves the oxidation of its conserved peroxidatic cysteine to sulphenic acid that is recycled by a reductor agent. The introduced iodine can subsequently serve as a handle for further functionalization such as introduction of fluorescent dyes and thus be used for chemoselective labeling of isolated peptides. Characterization of the Hoechst 33342 side population from normal and malignant human renal epithelial cells. However the concentrations of these steroids in the sera of these women were lower (15-179 ng/mL, 8-80 ng/mL, respectively).

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A detailed Web-based questionnaire was sent out to approximately 15,000 physicians across Europe and disseminated through partner websites. Although several prognostic indices have been identified that predict need for longer or more intensive treatment, few prescriptive indices have yet been established to select among the different treatments. This premise has prompted clinicians and researchers to consider opioid rotation as a valid tool for cancer pain management to increase the probability of acceptable adverse effects with adequate analgesia. This phenomenon is considered to be part of the fingerprint of recent climate change on the biosphere. The present study begins to address the paucity of research regarding end-of-life caregiving experience with dementia.

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Knockdown of ME1 or ME2 potentiated therapy-induced senescence in HNSCC cells regardless of p53 status, and led to increased p21 and generation of ROS. In this paper we would like to demonstrate that representations similar to CGR can be generalized and applied for visualizing and analyzing protein databases.

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A close relationship has been discovered between the magnitude of energy activity and bronchial patency. Use of ampicillin plus ranitidine for Helicobacter pylori gastritis.

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Although the link between Helicobacter pylori infection and gastric cancer is well established, little is known about the early development and detection of this malignant disease. To evaluate the diagnostic value of the PEDT and its association with intravaginal ejaculatory latency time (IELT).

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Patients with human immunodeficiency virus (HIV) infection on antiretroviral (ARV) therapy are at increased risk for medication errors during transitions of care between the outpatient and inpatient settings. An improved scoring function for suboptimal polar ligand complexes. In addition, the SSU rRNA gene of another rare, morphologically similar form, Euplotes rariseta, was sequenced. These results support the recently reported CEA-CEA homophilic reciprocal binding model in which anti-parallel molecules are bound by 2 bonds between the N domain of one molecule and the A3B3 domain of the interacting partner. Standard immunocytochemical techniques were used, to reflect the staining patterns likely to be seen in routine diagnostic practice.

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The lung parenchyma comprises a large number of thin-walled alveoli, forming an enormous surface area, which serves to maintain proper gas exchange. On the generation and outcome of 3-(N-phenylamino)propane-1,2-diol derivatives in deodorized model oils related to toxic oil syndrome. Northern blot analysis showed the 2.2 kilobase (kb) cathepsin D mRNA to be induced by estradiol in MCF7 cells and produced constitutively at high levels in the estrogen-receptor-negative BT20 cell line.

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The aim of this experiment was to determine if a task of associative olfactory learning, based on the ethological repertory of rats and learnt rapidly in 5 successive trials, could modify slow wave sleep (SWS) and/or paradoxical sleep (PS) duration after learning and/or after a retrieval-reactivation test 24 h later. Monitoring of mycophenolic acid in pediatric renal transplant recipients. Concomitantly, the expression of glial fibrillary acidic protein and alpha-smooth muscle actin indicated deactivation of hepatic stellate cells.

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Extravasation of leucocytes in tissues is mediated by leucocyte-endothelial cell interactions in which adhesion molecules play an important role. Activation of capsaicin-sensitive sensory fibers modulates PAF-induced bronchial hyperresponsiveness in anesthetized guinea pigs. One underlying mechanism is a sympathetically dominated autonomic imbalance.

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Genome-wide linkage scan for quantitative trait loci underlying normal variation in heel bone ultrasound measures. No deterioration is noticed in the coherence properties of the delivered signal, which attains frequency instability at the 10(-19) level in both cases. Of the 66 primary patients, 25 (38 percent) presented for reconstruction after recurrence following prior breast conservation therapy: 12 had prosthetic based reconstructions (with or without a latissimus flap) and 13 had autologous reconstructions.

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These cells are rarely or not at all replaced during life and can be as old as the whole organism. Application of image-guided radiotherapy in external beam radiation of cancer patients Associations of ABCB1 and XPC genetic polymorphisms with susceptibility to colorectal cancer and therapeutic prognosis in a Chinese population. The nonlinear structure of motion perception during smooth eye movements.

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We retrospectively reviewed the records of patients who underwent artificial urinary sphincter revision surgery between 1996 and 2013. Cox proportional hazards models in the derivation cohort to derive risk equations accounting for competing risks. The role of the interleukin-2 (IL-2)/IL-2 receptor pathway in MRL/lpr lymphadenopathy: the expanded CD4-8- T cell subset completely lacks functional IL-2 receptors.

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This mutant lacked all detectable ALDH activity, had lost the ability to grow with ethanol as a carbon source, but was unaffected in pathogenicity. Management of the patient with low back pain need not be particularly confusing, expensive, or invasive. It is pointed out that inherent differences exist among different types of cells and that environmental conditions of cells are important. Present study reports the preliminary phytochemical investigation of petroleum ether and ethanolic extracts of Cyclea peltata and their diuretic activity. CBCT scanning detect MRCMS more accurately than panoramic radiography.

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These findings indicate that chemoceptive, capsaicin-sensitive nerves are present throughout the whole rat lower urinary tract and their activation determines a variety of visceromotor responses and an increase of vascular permeability. The ZnO nanorods with ZnO microflower top layers were applied as photoelectrodes in dye-sensitized solar cells.

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This study describes demographic, residential, health, and utilization characteristics of patients over 70 years of age followed in a hospital-based teaching group practice. These engineered pseudoviruses were thus demonstrated to induce immune responses to both hepatitis E virus and human papillomavirus when they were administered to mice intramuscularly.

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We report two cases with HOS, first associated with renal agenesis, coronal hypospadias, urethral duplication and second associated with duodenal atresia and horseshoe kidney that have not been reported in English literature. In the organs to which melanoma cells metastasize, extravasation of melanoma cells is regulated by adhesion molecules, matrix metalloproteases, chemokines and growth factors. Synchronization of pancreatic islet oscillations by intrapancreatic ganglia: a modeling study. Retinal dystrophy patients and normal age- and gender-matched controls underwent FD-OCT imaging using the RTVue (Optovue Inc., Fremont, California, USA).