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A clear decrement in neurobehavioral functions as measured by the Psychomotor Vigilance Test lasted for 6 h after melatonin administration (particularly in the lapse domain and median of the reaction time) without any effect on a letter cancellation task. Recently it has been suggested, based on animal models, that periodontal ligament could be a niche for neural crest stem cells.

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The histopathological effect of preoperative irradiation in adenocarcinoma of the periampullary region Pregnant rats were given either BBP or DBP by gastric intubation at a dose of 0.75, 1.0 and 1.25 g/kg on days 7-9, days 10-12 and days 13-15 of pregnancy. It was asked whether discharge modulation of FEF pursuit neurons during head rotation on the stationary trunk could be accounted for by vestibular inputs only or if both vestibular and neck proprioceptive inputs contributed to the modulation. Using a transient expression system of mouse IgM mini-gene constructs in mouse B-cell lines and in fibroblast L cell, we investigated splicing of the IgM transcript. Together, these features falsify algal, lichen, and metazoan interpretations of these fossils, yet reflect characteristics of modern fungal mycelia.

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Midline cleft syndrome with sphenoethmoidal encephalocele: a case report. The method is simple and reliable and enables the simultaneous determination of the drugs in 600-microliter plasma samples with a sensitivity suitable for standard drug monitoring purposes. In this study we have used L6 muscle cells to investigate the mechanism by which the short-chain ceramide analogue, C2-ceramide, promotes a loss in insulin sensitivity leading to a reduction in insulin stimulated glucose transport and glycogen synthesis. We examined five clonally unrelated clinical isolates of polymyxin B-resistant P. Dietary intake of polyphenols and major food sources in an institutionalised elderly population.

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Complementary DNA clones for exogastrula-inducing peptides (EGIPs) of the sea urchin Anthocidaris crassispina, which are related to epidermal growth factor (EGF), were obtained from a cDNA library of late gastrula embryos using, as probe, the partial cDNA for one of the EGIP (EGIP-D) obtained by the reverse-transcription PCR method. Safety in hockey: cage versus molded masks for goalies, protective helmets for referees.

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Molecular toxicity of earthworms induced by cadmium contaminated soil and biomarkers screening. A good correlation was observed between these anthropometric measurements and the indices of pulmonary function. Increases in heart rate, peak heart rate and duration of action were similar with both drugs.(ABSTRACT TRUNCATED AT 250 WORDS)

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Cancer-related microRNAs and their role as tumor suppressors and oncogenes in hepatocellular carcinoma. During the first infusion, histamine release peaked at 179 ng/min, whereas, during the second infusion, histamine peaked at 125 ng/ml. The purpose of this study was to evaluate the effects of reduced masticatory muscle activity on the jaw bones of adult rats.

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Comparison of high-resolution melting analysis, TaqMan Allelic discrimination assay, and sanger sequencing for Clopidogrel efficacy genotyping in routine molecular diagnostics. In the past decade, their interaction with various biological models, ranging from isolated cells and tissues to small animals, has been extensively investigated. AGE enhanced the calcification potentials of rat dental pulp cells, suggesting that it may stimulate pathologic calcification of diabetic dental pulp tissues. Inhibition of inducible NO synthase was also found with the same drug concentrations.

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Organized data management increases the reliability of statistical analysis. Reproductive parameters following a PRRS outbreak where a whole-herd PRRS MLV vaccination strategy was instituted post-outbreak. The creation of a test system for detecting Mycoplasma pneumoniae based on a method of directed DNA amplification

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The effects of ATPgammaS on HIV-1 reverse transcription appeared to be indirect, resulting from disruption of virion core morphology that was evident by transmission electron microscopy. The results suggest that adipocytic conversion of human SF by KiMSV and DX is specific. Interventions are needed to ameliorate stress that does not cause adverse effects.

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xylostella, and for further understanding of their physiological roles and regulatory pathways in insecticide resistance. The distinction between these two tumors is important because only hepatic adenoma carries a significant risk of complications (bleeding or hepatocellular carcinoma) leading to surgical resection of lesions that do not regress after steroid withdrawal. Purified CD34-positive BM cells, cultured for 12 to 14 days with granulocyte colony-stimulating factor (G-CSF), differentiate into a population of mature granulocytic cells. Cyt2Aa2 is a mosquito larvicidal and cytolytic toxin produced by Bacillus thuringiensis subsp.

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They emphasize importance of cooperation between particular departments in complicated postoperative wound therapy management. Phylogenetic relationships among russuloid basidiomycetes were investigated using sequence data from the nuclear 5.8S, ITS2 and large-subunit rDNA genes. Environmental pollutants may have contributed to the rising global obesity rates. However, it is known that menaquinones (vitamin K2:MK) may be more effective than vitamin K1 in this conversion of the inactive to active form of glutamate residues.

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We first describe the impact of altered epigenetic regulation in non-CKD-associated arteriosclerosis, and next characterize uraemic features which may affect epigenetic gene regulation in the context of cardiovascular disease. At the later stages of the disease ambulation often becomes difficult, with owners often electing to euthanise affected dogs on welfare grounds.

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Resolving the negative data publication dilemma in translational stroke research. Linear processes in high dimensions: Phase space and critical properties. In addition, LPS and MDP activated synergically the production of interleukin-I by spleen cells in vitro. NMDA receptors mediate neuronal burst firing in rat somatosensory cortex in vivo.

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Macrophage inhibitory cytokine-1 (MIC-1) belongs to the transforming growth factor (TGF)-beta superfamily, and has been reported to be involved in energy homoeostasis and weight loss and to have anti-inflammatory properties. Distribution in human CSF was confirmed, but the free concentration of the drug was below that associated with biologically relevant target inhibition. This method incorporates some of the desirable components of previously reported techniques, while eliminating difficult and unreliable aspects of those same techniques. The pressure distributions at the geometric center and at off-center positions were tested experimentally. To clarify the significance and role of anaerobic bacteria in postoperative infection, we retrospectively analyzed cases in which postoperative infection by these organisms developed.

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These findings suggest an immunological basis for the disease and indicate that the patients should be investigated and followed up to detect the existence of other auto-immune disorders. Differential diagnosis includes X-linked adrenal hypoplasia congenita, a genetic disease characterized by an alteration in the formation of the adrenal glands and the hypothalamus-pituitary-gonadal axis. A successful method for the analytical subcellular fractionation of mouse duodenal mucosa organelles was established. Improvement of recombinant protein production with the human adenovirus/293S expression system using fed-batch strategies.

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We have cloned a new member of the sialyltransferase gene family from newborn rat brain cDNA using the polymerase chain reaction and degenerate primers based on sequences found in a continuous region of homology present in three previously cloned sialyltransferases. An improved method for the isolation of eosinophilic granulocytes from peripheral blood of normal individuals. No treatment-related changes were observed in any dam treated at 300 mg/kg/day or less. An important area for further research is the interpretation of the outcome of HRQL measures.

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Staff at a nurse-led gynaecology oncology clinic performed an audit that found the clinic was not meeting the longer-term needs of most women after radiotherapy for endometrial griseofulvin child dose cancers, and that women were attending multiple appointments to access different services. The measurement of an optimal birth space is currently impossible, because limited tools are available.

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