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To this end, an approach to holistic care process-support requirements elicitation is presented which is based on business process modeling and places particular emphasis on empowering collaboration, coordination and information sharing among health and social care organizations by actively involving users and by providing insights for alternative process designs. Lepromatous meningoencephalitis in the nine-banded armadillo (Dasypus novemcinctus).

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To further understand the bi-lobe and its association with adjacent organelles, we performed proteomic analyses on the immunoisolated bi-lobe complex. Synthesis of junctional proteins in metastasizing colon cancer cells. The limit theorem for sample moments is derived by showing that the moment conditions can be recast such that a martingale difference array central limit theorem can be applied.

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Initially ethical guidelines in medicine were aimed at protecting the interests of trial participants. Functional dissection and module swapping of fungal cyclooligomer depsipeptide synthetases. Clinical and radiographic 5-year data were collected for the test and control groups. Hb A2-Parkville or delta 47(CD6)Asp----Val, a new delta chain variant.

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tsJT60 is a temperature-sensitive (ts) mutant of the cell cycle isolated from a rat cell line. A further association between VDR polymorphisms (in linkage disequilibrium) and the presence of specific characteristics of these diseases, in particular the formation of osteophytes, was evidenced. Rabbits were first immunized and later challenged with the same antigen (bovine serum albumin, or ferritin) by injection into the tibialis anterior tendon. This disorder shares some clinical and laboratory findings with pre-eclampsia, including thrombocytopenia.

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A statistically significant correlation was found between FPL and the extent of the RRD, even if the influence of the number of breaks was excluded. Recent advances in endoscopic diagnosis and treatment have led to better prognosis for patients with superficial oesophageal cancer. Postoperatively, new-onset acute right lumbar radicular syndrome developed and the postoperative MRI scan confirmed a far lateral extraforaminal disc herniation at L5-S1 with compression of the right nerve. Further, these studies point to the importance of resolving the location of metabolites in addition to their quantities within plant tissues. The odds ratios (ORs) for recurrent strokes were derived using multivariate logistic regression models, based on deep MBs and risk factors.

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The divergent results produced by the two steroids could not be attributed to differences in rates of catecholestrogen generation in the culture medium or by the conceptuses. The purpose of this study was to evaluate the clinical relevance of high values of central venous-to-arterial carbon dioxide difference (PCO2 gap) in high-risk surgical patients admitted to a postoperative ICU. Cells positively stained for cytokeratins could be seen near to other cells which were negative. Measurements made on a port wine stain, which had been treated with 576 nm CW laser radiation at times between 1 and 6 months previously, provided information on the vascular response to this thermal injury.

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We have shown, in addition, that Cys-117 is involved in the formation of a disulfide-bonded homodimer of GRP94. Two new uracil derivatives, sorivudine and BW882C87, with increased anti-varicella-zoster virus activity in vitro are also being studied.

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Lovastatin (Mevacor) 20 mg is being considered for nonprescription availability. Evaluation of the effectiveness of a specific immunoglobulin against hepatitis A Ischemic-reperfusion injury of the heart: comparison of intra- and extracellular types of cardioplegic solutions Further samples to explore regional and cultural adaptations should be evaluated. We discuss the implications of these findings and consider how they may inform future studies on biomarkers for cognitive and affective risk factors for anxiety.

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Artesunate reduces but does not prevent posttreatment transmission of Plasmodium falciparum to Anopheles gambiae. The study was conducted at the Yale Center for Clinical Investigation Hospital Research Unit, Yale Magnetic Resonance Research Center.

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Kinematic variables can be used as outcomes in clinical trials to test upper limb intervention effectiveness on motor performance and movement quality. The contributions of MMP-9 and TIMP-1 to the early stages of ACI are not completely understood.

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Cardiovascular events are the main cause of morbidity and mortality in uremic patients on renal replacement therapy. Studies of peritoneal fluid were rarely helpful and cell counts overlapped in the cases and controls. Noncardiac surgery is becoming more common in patients with LVADs. A perineal eruption was observed in 17 cases and was found of good diagnostic value even though not pathognomonic. The activity of the coral Stylophora pystillata secretory carbonic anhydrase STPCA has been tested in presence of amino acids and amines.

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Molecular background and clinical characteristics of HNF1A MODY in a Polish population. Vanadium toxicity in mice: possible impairment of lipid metabolism and mucosal epithelial cell necrosis in the small intestine. Integrin beta 1 (beta1-integrin), the protein encoded by the ITGB1 gene (also known as CD29 and VLAB), is a multi-functional protein involved in cell-matrix adhesion, cell signalling, cellular defense, cell adhesion, protein binding, protein heterodimerisation and receptor-mediated activity. Nucleating activity did not change discernibly throughout interphase but increased approximately fivefold at the transition to mitosis.

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It also maintains the structures in regions with gradual intensity transition more successfully. A method for calculating a coefficient of inbreeding and specific weight of an ancestor in an animal pedigree

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Consensus was observed on core content, underpinning philosophy and professional identity across institutions. Given that transfer of CNS-specific CD8 T cells results in an attenuated clinical demyelinating disease in C57BL/6 mice with immunization-induced experimental autoimmune encephalomyelitis (EAE), we investigated the cellular targets and mechanisms of autoreactive regulatory CD8 T cells.

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Sensory segmental latency values of the median nerve for a population of normal individuals. Experimentation revealed that predator functional diversity effects propagated down the live plant-based chain to affect the levels of plant diversity, and plant litter quality, elemental cycling, and production. To examine whether aromatase inhibition with Letrozole can normalize serum testosterone levels in severely obese men with hypogonadotropic hypogonadism. This was a cross-sectional study involving 144 individuals: 51 asthma patients, 53 COPD patients, 20 current smokers, and 20 never-smokers.

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There was no significant difference in fatigue and mechanical power. What are the effects of medical treatment in people with acute ischaemic stroke? Low-loss amorphous silicon wire waveguide for integrated photonics: effect of fabrication process and the thermal stability.

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Orthotopic syngeneic kidney transplantation was performed in Lewis rats following 24 h of cold preservation in University of Wisconsin solution equilibrated without or with CO (soluble CO levels about 40 microM). Staphylococcal purpura fulminans may be a newly emerging illness associated with superantigen production.

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This review summarizes the cellular substrates responsible for the coordinated interactions between the nervous and vascular systems and how this relates to gliomagenesis. The toxicity was dependent on iron-mediated free radical formation, since the iron chelator, deferoxamine, and the antioxidants, promethazine, butylated hydroxytoluene, and dithiotreitol, prevented the lipid peroxidation, the mitochondrial dysfunction, and cell death.

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Chromosome aberrations in tenosynovial giant cell tumors and nontumorous synovial tissue. Possible dominant-negative mechanisms, which affect the processing, translocation or degradation of wild-type rhodopsin, are also considered. Analysis about the influence on the fetus infected with parvovirus B19 using amniotic erythropoietin and troponin-T. We aimed to identify other neuroanatomical substrates of both cognitive dysfunction and IED in patients with TLE, with special focus on the cerebellum, a brain region known to participate in functional networks involved in neuropsychological and affective processes.

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This suggests that epoetin beta with IV iron is a dominant therapy from a Swedish perspective. Study patients were 18 years or older, untreated, and newly diagnosed with celiac disease by serum markers and jejunal biopsy. Two mouse monoclonal antibodies (mAb) generated to the M antigen of Brucella melitensis 16M were analysed.

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Experiments were performed in cultured monolayers of human umbilical vein endothelial cells (HUVECs). Functional reconstitution of purified sodium channels from brain in planar lipid bilayers. Rapid detection of rifampicin- and isoniazid-resistant Mycobacterium tuberculosis by high-resolution melting analysis.

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Space planning and renovation: aids to a more productive optometric office. Furthermore, the digested microtubules gave rise to the same change in turbidity per polymer mass as that found for normal microtubules.

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We further show how to interpret and analyze the large amount of sequencing data that is generated in RNA-seq. In an attempt to improve this, high-dose intraarterial 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) was utilized on 41 patients with these neoplasms over a 4-year period at our institution. We investigated the clinical factors predisposing moderately or poorly differentiated hepatocellular carcinoma and analyzed which clinical and histological factors are associated with poorly differentiated hepatocellular carcinoma (HCC) recurrence. We tested the hypothesis whether selective blunting of platelet-derived growth factor (PDGF)-dependent vascular smooth muscle cell (VSMC) proliferation and migration is sufficient to prevent neointima formation after vascular injury. Identification of novel adenosine A(2A) receptor antagonists by virtual screening.

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The purpose of this study was to identify pharmacological agents that would inhibit apoptosis in HL-1 cardiomyocytes expressing E334K cMyBPC. The BOK-deficient mice have no readily discernible abnormalities, and its function therefore remains unresolved. Presence of argyrophilic cytoplasmic and nuclear proteins in the spermatic cells of Nucella lapillus (Gastropoda, Prosobranchia). Up-regulation of p27Kip1 protects hES cells from differentiation-associated and caspase 3-dependent apoptosis. Cell survival assays were performed, profibrotic PAI-1 expression was monitored by quantitative polymerase chain reaction, and apoptosis was assayed by annexin V staining.

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This method consists in determining for each individual what is the most likely couple of parent pair amongst all older individuals, according to some probability measure. Dose titration of IVIg is necessary to avoid over- and undertreatment.

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We investigated the activity of matrix metalloproteinase (MMP)-2 and -9 and their latent pro-forms (proMMP-2, -9), and protein levels of MMP-1, -3, -8 and tissue inhibitor of MMPs (TIMP)-1 in the subretinal fluid (SRF) and vitreous of patients with rhegmatogenous retinal detachment (RRD). To find out the incidence of Acinetobacter infection in VAP cases, to determine various risk factors responsible for acquisition of Acinetobacter infection and to determine the antimicrobial susceptibility pattern of Acinetobacter. The leader sequence appears to be highly conserved for both isoforms and shares a complete similarity with the partial hirudin variant 2 (HV2) signal peptide sequence previously reported. These results indicate that processing of the precursor to the 34-kDa polypeptide occurs in an acidic compartment(s) possibly in either the trans Golgi network, or condensing vacuoles or both.

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The present paper reports an investigation of the relationship between psychological hardiness and health behavior. We have tried a percutaneous endoscopic transforaminal approach through minimal one portal skin incision and remove the two herniated disc materials in the adjacent levels. In this study we investigated brain regions that are known to be implicated in the neurobiology of suicide and major depression are likely to represent valid global molecular alterations.

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Analysed guidelines included WHO, European Network for Public Health Nutrition, US and two European national guidelines (UK and France). Physicians must pay special attention to infants with complex CHD because they are at high risk for the development of VAP after congenital heart surgery.

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in individuals sustaining a blow to the periocular area and presenting with ocular symptoms, although with minimal soft tissue signs of trauma. YB-1 DNA-binding protein represses interferon gamma activation of class II major histocompatibility complex genes. In this study, we sought to determine whether obese patients with polysomnography-confirmed diagnosis of OSA were at significantly greater risk for postoperative hypoxemic episodes in the first 24 h after laparoscopic bariatric surgery than morbidly obese patients without a diagnosis of OSA.