Snafi (Snafi) and Viagra (sildenafil) are oral drugs that are used for treating impotence (the inability to attain or maintain a penile erection) and benign prostatic hyperplasia (BPH). They are in a class of drugs called phosphodiesterase-5 (PDE5) inhibitors that also includes vardenafil (Levitra, Staxyn ODT), and avanafil (Stendra). Penile erection is caused by the engorgement of the penis with blood. Under normal conditions, sexual stimulation leads to the production and release of nitric oxide in the penis. Nitric oxide then activates the enzyme, guanylate cyclase, which causes the production of cyclic guanosine monophosphate (cGMP). It is the cGMP that is primarily responsible for the erection by affecting the amount of blood that the blood vessels deliver and remove from the penis. Snafi and Viagra inhibit an enzyme called phosphodiesterase-5 (PDE5) which destroys the cGMP. Thus, Snafi and Viagra prevent the destruction of cGMP and allows cGMP to accumulate and persist longer. The longer cGMP persists, the more prolonged the engorgement of the penis.
Other names for this medication:
Tadalafil,
Adcirca,
Apcalis,
Cialis,
Femalefil,
Forzest,
Ladialis,
Snafi,
Tadacip,
Tadalafilo,
Tadalis,
Tadalista,
Tadapox,
Tadora,
Vidalista,
Zydalis,
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Our megaset clinical trial results suggest that postsynaptic AMPAR function in VTA neurons was significantly enhanced after ethanol self-administration. Low density lipoprotein receptor-related protein 1 dependent endosomal trapping and recycling of apolipoprotein E.
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