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The alterations in short-ear mice are confined to particular skeletal features and a human equivalent is not known. In this study, bovine hoof was used as recalcitrant protein model to gain so far cryptic information on biodegradation during livestock mortalities composting.

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The arrest, retention, and elimination (i.e., clearance) of radiolabeled YAC-1 lymphoma cells injected either iv or into the left ventricle (LV) of the heart were studied in male BALB/c mice, with special emphasis on the role of natural killer (NK) cells. Radiotherapy was delivered to the chest wall with a dose of 50 Gy in 25 fractions over 5 weeks.

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Other typical manifestations of the syndrome involving the facial midline are also present. Hepatotoxicity was assessed histologically and by measuring plasma alanine aminotransferase (ALT) activity. Two hundred and ninety six adolescents aged 14-18 years attending an urban school in the province of Buenos Aires were surveyed and clinically studied. Phenothiazines inhibit hepatitis C virus entry, likely by increasing the fluidity of cholesterol-rich membranes.

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Knee osteoarthritis (OA) is a chronic condition characterized by pain, stiffness and functional limitations. Only in monkey, cholinergic putative preganglionic neurons were found within the cytoarchitecturally defined EW, whereas in rat, ferret, and human the EW is almost exclusively composed of urocortin-positive neurons. The data also show that genomic recombination between different conspecific lineages can rapidly carry the combined lineage to a higher peak. Differential mammary gland development in FVB and C57Bl/6 mice: implications for breast cancer research.

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Based on our recent finding that CD23 interacts with CD21 on subsets of B and T cells, we investigated if the same ligand was involved on KU 812 cells. Joubert syndrome and related disorders: spectrum of neuroimaging findings in 75 patients.

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All mice were perfused and fixed for immunohistochemical analysis after finishing the kindling experiment. Analysis of leaf development demonstrated that maize primordia initiate more rapidly relative to blade and sheath growth than do either bluegrass or rice. In order to express its biological activity, PAF and its metabolites are transported among subcellular membranes by as yet unexplained mechanisms.

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The chemical nature of the gastrointestinal insulin-like material and its physiological role remain to be determined. Diabetes as an independent predictor of high atherosclerotic burden assessed by coronary computed tomography angiography: the coronary artery disease equivalent revisited. AFG at doses of 5 and 10 mg/kg/day significantly reduced the fungal load in kidney of mice, but only the higher dose was able to prolong survival. The effects of prenatal education intervention on unwed prospective adolescent fathers.

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Here, we performed a meta-analysis on published data sets of in vivo microdialysis measurements to assess the concentration-dependent effects of EtOH on monoamine levels within 19 distinct brain regions in adult rats, which were identified as major components of a neurocircuitry for modeling drug effects. Role of Ess1 in growth, morphogenetic switching, and RNA polymerase II transcription in Candida albicans. Initial contraction was significantly attenuated by superoxide dismutase (SOD), methylene blue, but not by catalase. In addition, scanning tunneling microscopy was used to monitor surface-directed Ullmann coupling of 2,8-dibromo-dibenzothiophene (DBDBT) molecules on s-MoSx nanosheets, where the four-fold symmetric surface sites on s-MoSx direct C-C coupling to form cyclic tetramers with high selectivity.

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relapse of nycturia and consequently of sleep disturbances) could have indirect effects of cognitive function. Variations of Gd-DTPA transport through the blood-inner ear barriers induced by mitochondria toxin was visualized in guinea pigs using a clinical 3.0 T machine.

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Apoptosis and oncotic necrosis in neuronal and glial cells have been documented in many neurological diseases. The haemodynamic conditions in bone depend upon blood flow and resistance. A deletion mutant of stefin B, corresponding in length to the carboxy terminal sequence of chicken cystatin, was constructed by the use of polymerase chain reaction (PCR).

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In contrast, complete denudation of the epithelium were still evident along most of the length of the irradiated segments in rats receiving 40 or 50 Gy. We report detailed clinical and virological data for two related cases of MERS-CoV disease, after nosocomial transmission of the virus from one patient to another in a French hospital. Raising numbers of elderly lead to a dramatic shift in demographics, accompanied by an increase in non-communicable diseases such as cancer, cardiovascular disease and dementia.

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This result suggested that TolC contained a binding site for peptides. We carried out neurological deficit assessments, infarct volume measurements, histopathological examinations, and immunohistochemistry analyses. Ablative cesarean section and post-partum hysterectomy: review of 11 years of obstetric practice Vessel alterations in the retina are associated with several human diseases and the retina has been intensely used for angiogenesis studies, whereas the choroid has been much less investigated.

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The pharmacology of anticonvulsant drugs is reviewed with emphasis placed on the treatment of canine and feline epilepsy. Of the total 161 patients studied, 26 displayed no cardiac disorder. The role of humoral factors in the pathogenesis of gentamicin and tobramycin aminoglycoside-induced acute renal failure was studied in rats. In patch-clamp experiments using rat cortical neurons in culture, HA-966 blocked the potentiation of NMDA responses by glycine but had little effect on basal NMDA responses themselves.

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Protozoan parasites, such as Leishmania, still pose an enormous public health problem in many countries throughout the world. Following a review of the different approaches as well as recent findings in research, the present study outlines a possible route to the development of mental illness starting from a genetically determined more general vulnerability leading to non-specific cognitive dysfunct on in early childhood on to an impaired synchronicity finally leading to a distancing from external reality in the form of overt psychotic symptoms.

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Total synaptic and extrasynaptic GluA1 expression remained stable in the two regions after AMPH administration. The charts of all patients who underwent right colectomy by a totally laparoscopic approach in our service since 2004 were reviewed and pre-, intra-, and postoperative data were collected.

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Clinical and experimental studies of the combined use of dibasol and furosemide Clinical study of epileptic children with history of febrile convulsion. So far, in theoretical as well as in field studies, this relationship has received only scant attention.

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Upon Wnt stimulation, beta-catenin heterodimerizes with T-cell factor (TCF) DNA-binding proteins to form a transcriptional activator complex. These results are discussed in relation to proposed mechanisms of action of strophanthidin and more generally in relation to the factors linking force of contraction and aiNa. Three hundred and fifteen ears (217 ears with cholesteatoma and 98 with chronic otitis media) undergoing mastoidectomy with or without tympanoplasties were selected for retrospective study, in which the incidence and locations of FND was studied, and the relevance for FND were analyzed by univariate test following by multivariate stepwise logistic regression. Structural Insights into IRE1 Functions in the Unfolded Protein Response.

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Differential induction of cytolytic susceptibility by E1A, myc, and ras oncogenes in immortalized cells. Methionine residues are susceptible to oxidation, but this damage may be reversed by methionine sulfoxide reductases MsrA and MsrB. One complication mentioned by interviewees is that as organ transplantation is a relatively new medical procedure, there is no explicit reference to it in many original religious texts.

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Mithramycin, a G-C specific DNA binding drug, prevents the increased transcriptional activity of c-myc and c-Ha-ras genes after hepatectomy but does not alter the transcriptional activity of the beta-actin gene. Pregnancy by procreative medical assistance at over 60 years, is this involuntary age discrimination? The most striking features of this comparison are the presence of Ala instead of Ser(329) and the presence of Thr instead of Asn(256) and Ala(299), in the subtilisin-like region of the CEP in LBP natural isolates. Four women suffering from polycystic ovary syndrome recalcitrant to routine ovulation inducers have been submitted to electro-cauterization and ovarian resection.

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Care of HIV-infected people in the developing world: practical aspects. This paper discusses a transformation algorithm, its properties, and develops statistical methods to detect clustering of cases around a fixed point for data plotted on DEMPs. Thus, iterative solution schemes can be successfully implemented for solving the electrical double-layer interactions for very large and complex systems. Kallikreins release kinins which are the biological active compounds of the kallikrein-kinin systems.

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The percentage of patients achieving serum uric acid levels 6.0 mg/dL or less and the percent change in serum uric acid levels after 16 weeks of treatment were evaluated. Avulsion fractures of the tibial tuberosity are typically sustained by adolescent males during sporting activities. Physical examination, electrocardiography, coronary angiography, echocardiography, cardiac computed tomography. The microbial mechanisms controlling the initiation and progression from mild skin infection to a severe disseminated infection remain poorly understood.

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In this paper we describe a new mass spectrometry data library, and a novel method to efficiently index and search in the library for spectra that are similar to a query spectrum. Stimulation of the penile or pelvic nerves increased intracavernous pressure. Obesity has a negative impact on NAFLD at all aspects and stages of the disease. Our data provide support for the hypothesis that WK, particularly in combination with quinidine, effectively suppresses arrhythmogenesis in an experimental model of BrS via inhibition of Ito and indirect adrenergic sympathomimetic effects. Longitudinal changes in plasma cholesterol and triglyceride levels in Japanese male workers, 1977-1992.

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The tumors were then excised, and histologic evaluation was performed by using an immunofluorescence-tagged monoclonal antibody against blood vessel endothelium. Our photobleaching experiments show that MET exists in dimers on the membrane of cells in the absence of ligand and that the proportion of MET dimers increases significantly upon ligand binding. Symptomatic vaginal candidosis did not occur in any patient during regular maintenance treatment. Accelerated liver fibrosis in hepatitis B virus transgenic mice: involvement of natural killer T cells.

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Incidence of rhabdomyolysis and subsequent renal dysfunction was calculated. Content-addressable-memory-based single-stage optical modified-signed-digit arithmetic. These results suggest that the high level of corticosterone released by immature nestlings in response to a stressor may promote anti-predator behavior (e.g., passive avoidance behavior). In these cells, the combination treatment with TSA and PCA exhibited stronger reduction of the viability.

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