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In the continuous infusion group, the total 5-day exposure to filterable platinum, determined from the area under the concentration-time curve, was 1.5 to 2-fold higher (P less than 0.01) than that observed in the intermittent bolus group although the maximum filterable platinum concentration achieved was 8-fold lower (P less than 0.01). First, as a common employed in vitro model, profile of HepG2 is shown. Precipitating factors that contributed to perforation were identified in all patients. The purpose of this systematic review was to compare the attitudes of dentists and dental hygienists towards extended scope and independent dental hygiene practice.

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The present studies demonstrate that morphine can increase, decrease, or not affect plasma catecholamines depending on the dose and on the experimental conditions under which it is given. Since it was first observed by Shennan in 1915 only fifty-five cases have been reported in the literature (Rondier et al., 1977). This is the first method that provides accurate size distributions of E. Effectiveness of a rapid immunohistologic method for tumor cell origin analysis. In this review, we discuss the side effects associated with bevacizumab and potential treatments to ameliorate these toxicities.

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Group 1 consisted of five patients with chronic complete atrioventricular block (CAVB) who had narrow QRS complexes and AH block (block proximal to the His bundle deflection). The management of early-onset scoliosis is challenging, with many treatment options but no conclusive evidence for the best treatment method. We concluded that ZIP9 regulates cytosolic zinc level, resulting in the enhancement of Akt and Erk phosphorylation. He was transferred to the Intensive Care Unit (ICU) on a ventilator, which was soon removed and the patient was off vasopressors, with stable vitals for 24 hours after the event.

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The diagnosis of Potorolepis and a list of species included are given. Additional nontemporal stimulation during waiting affected the behaviour of all children for most behavioural characteristics. The abilities of various asymmetrical arm and hip techniques to produce twist during flight were investigated using 10 simulations to maximise twist and allow reorientation prior to landing. The effect on expression of platelet-derived growth factor (PDGF), a potent mediator of vascular smooth muscle cell migration and proliferation and its receptors was also investigated. Stranski-Krastanow strained islands undergo a shape anisotropy transition as they grow in size, finally evolving toward nanowires.

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Concerns have therefore been raised with regard to the evolution of the resulting pregnancies and long-term outcome of the children born. We first discuss how we select aptamers against live cancer cells. They appear only above a high-bias threshold at the scale of electronic nanotube excitations.

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These two distinct classes of neurotrophic factors, utilizing distinct signaling pathways, can interact to effect the growth and differentiation of neuronal progenitors during neuropoiesis in a way analogous to that exhibited by the cytokines during hematopoiesis. Considerable research in the field of immunotherapy for melanoma has demonstrated that this tumor type can be responsive to therapeutic immune activation strategies. The epithelial DHT level of NPR and BPH decreased with age, the correlation being statistically significant. The clinical-epidemiological characteristics of patients who were diagnosed of spontaneous infectious spondylodiscitis (SIS) in our Internal Medicine Department are analyzed and the related factors associated with the increase of the incidence are evaluated.

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Pathways by which supplementation with fortified foods may enhance dietary diversity, such as an improved appetite and increased body size, need elucidation. Automatic implantable cardioverter/defibrillator: inadvertent discharges during permanent pacemaker magnet tests. The trypsinized coat protein has lost the capacity of the native coat protein to make the genome RNAs of alfalfa mosaic virus infectious or to interfere with the infectivity brought about by the native coat protein.

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The patient supply is the most critical factor in the context of university clinic operations. Mice from a heterogeneous stock were selected for differences in ethanol-induced loss of righting reflex. (2) Preserved functional recovery after multidose warm blood cardioplegia suggests that repetitive episodes of ischemia may condition the myocardium, thus preventing injury during prolonged aortic cross-clamping.

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The presence of hormone receptors in laryngeal tumors raises the possibility that such gender-related differences are hormone-dependent. Aggregate risk study of exposure to endophyte-infected (Acremonium coenophialum) tall fescue as a risk factor for laminitis in horses. The protein lambda(6-85) has been implicated in barrierless folding by observations of kinetic relaxation after nanosecond T-jump. Branching pattern of inferior mesenteric artery in a black african population: a dissection study.

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Regional nodal failure was diagnosed by clinical and/or radiologic examination. Implementation of a transfusion algorithm to reduce blood product utilization in pediatric cardiac surgery. Whole tendon transfer may be an effective and simpler alternative to SPLATT for unloading the lateral forefoot in both a normal and a spastic foot.

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We report a case of a 45-year-old woman who had a palpable mass in the left lower quadrant of the abdomen. Elastin is the polymeric, extracellular matrix protein that provides properties of extensibility and elastic recoil to large arteries, lung parenchyma, and other tissues.

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The HD-CPB and ID-CPB arms were balanced regarding patient characteristics. During tissue ablation, laser light can be delivered with high precision in the transverse dimensions but final incision depth can be difficult to control. Of 24 sera recognizing only BPAG2, 20 showed the epidermal pattern and four stained both the epidermal and dermal sides (combined pattern). To evaluate the efficacy and the safety of combined 5-Fluorouracil, irinotecan, bevacizumab and sirolimus in refractory advanced colorectal carcinoma.

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Adjunctive Lanicemine (AZD6765) in Patients with Major Depressive Disorder and History of Inadequate Response to Antidepressants: A Randomized, Placebo-Controlled Study. The development and functional characterization of genetically modified mice that lack or overexpress genes that are involved in repair, combined with gene-expression analysis in wounds and tumours, have highlighted remarkable similarities between wound repair and cancer. To investigate alterations of endothelial progenitor cells (EPCs) from peripheral blood in patients with coronary heart diseases. The extracted DNA was obtained in sufficient quantity and purity to allow direct detection of transgene by PCR.

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In an in vitro rat tail artery helical strip assay, dibutyryl cAMP produced dose-related relaxation in arginine vasopressin (AVP) constricted blood vessels. High-throughput functional genomics approaches have provided insight into the mechanisms of CMV replication, but although CMV latency cell models have been useful in elucidating the mechanisms of viral latency and reactivation, omics approaches have proven challenging in these cell systems. Prior to the initiation of preventive therapy for tuberculosis, it is essential to rule out active TB. XRD and FTIR analyses confirmed the crystals were hydroxyapatite.

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This is a large epidemiological survey of patients with allergic rhinitis showing a strong relationship between disease severity, as assessed by a consensus classification, and sleep impairment, as measured by a validated sleep quality tool. Expression of early growth response gene-1 in precancerous lesions of gastric cancer.

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The procedure combines the great sensitivity of the polymerase chain reaction, the specificity provided by allele-specific molecular beacons, and the throughput of a multicolor fluorescence detection procedure. The analysis of event history data: a review of progress and outstanding problems. This paper examines parental reputation formation in intra-familial interactions.

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A fixed difference at one of nine enzyme loci surveyed confirmed the existence of two reproductively isolated, sympatric species. A comparison of wild-type, old and modern tomato cultivars in the interaction with the arbuscular mycorrhizal fungus Glomus mosseae and the tomato pathogen Fusarium oxysporum f. Results revealed a strong positive correlation between the personality trait Neuroticism and scores on the OASES. A 70-year-old patient with bilateral vocal cord paralysis, accompanied by inspiratory stridor and increased snoring, is presented.

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Based on the pleiotropic beneficial effects of statins, we examined whether simvastatin (SIMV) increased the efficacy of mesenchymal stem cell (MSC) transplantation after AMI. The tendency of GCH to involve the lower lobe of the lung compared to smaller cysts suggests underlying mechanisms other than lung elasticity in the late onset of the symptoms parallel to cyst growth. Clinical and radiological examination was done in three individuals in the family studied, which showed variation in expression of colour and attrition. The CBCT findings were compared with the corresponding panoramic images. After methacrylation, the monomeric dyes can be covalently emplaced into several copolymers.

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Current recommendations underscore the importance of early management of prediabetic stages (such as impaired glucose tolerance), early diagnosis and early pharmacologic intervention, achievement of target plasma glucose levels, and use of a regimen designed for the individual patient. Natural course of temporomandibular disorders with low pain-related impairment: a 2-to-3-year follow-up study. A 32-year-old female patient with MCTD who had developed rapidly progressive pulmonary hypertension and disseminated intravascular coagulopathy was admitted to our hospital and was successfully treated with corticosteroids and anticoagulants. The anastomosis angle is a key to improved long-term patency of proximal femoropopliteal bypass. We investigated allelic losses in microsatellites in the RAD51 and BRCA2 regions, and their association with clinicopathological parameters in breast cancer.

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The possibility of injury to the circumflex coronary artery was reduced using this surgical approach. Statements were based on systematic literature searches using the best-available evidence from PubMed, Cumulative Index to Nursing and Allied Health Literature, and bibliographies.

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The first method has been used in toxicokinetic studies of sulphur mustard and the second method is intended to be used for the retrospective confirmation of mustard poisoning in casualties of chemical warfare. Standardized mortality ratios (SMRs) for suicide, cardiovascular disease, and pneumonia were calculated and compared with patient demographic and clinical characteristics. Baseline clinical data were noted at admission and twice a day during follow-up, and laboratory analyses (with troponin testing) were performed.

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Pancreatic ductal adenocarcinoma (PDAC), a particularly aggressive malignancy, has been linked to atypical levels, certain mutations, and aberrant signaling of G-protein-coupled receptors (GPCRs). We report a family (male index case, mother and maternal grandfather) with autosomal dominant inheritance of paroxysmal exercise-induced dystonia.

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Association between a low ankle-brachial index and dementia in a general elderly population in Central Africa (Epidemiology of Dementia in Central Africa Study). The departments of radiology and anatomy: new symbiotic relations? Effectiveness comparison between arthroscopic and nonsurgical treatments for ankle degenerative osteoarthropathy

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The large-scale layer of the reference image is filtered with the guidance of the input image by guided filter with adaptive smoothing parameters according to the face structures. Five pediatric patients who presented with hip contractures are described. The NSF is broad, addressing the work of doctors, social workers and nurses, among others. It is suggested that glucose in the cell produces a hyperosmolar state which results in the rapid diffusion of water into the cells in the counter. Structural tracking of the potassium-mediated magnesiation of anisole.

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Serological and biochemical characterization of HLA-A molecules bearing a public epitope. Amebic colonization appears to respond completely to IUD removal, and there is no need for additional medical or surgical treatment. A systematic review on how medical registries provide information feedback to health care providers. However, the molecular mechanisms governing virus long-distance movement are far from being understood. Gastric leiomyoblastomas are rare tumors between leiomyomas and leiomyosarcomas in terms of their malignant potential.

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Previous research has found that many patients with anorexia nervosa (AN) are unable to maintain normal weight after weight restoration. Evolution equations for moments of order 1 and 2 - resulting from the equation of the generating function-are also discussed on the ground of certain simplifying hypotheses. Radiographic follow-up of suspected pneumonia: survey of Society of Thoracic Radiology membership. The use of neuroimaging in chiasmal or perichiasmal lesions and the natural history and treatment of optic nerve and chiasmal gliomas are discussed. We also evaluated breast development and testis volume in male to female subjects and clitoris length in female to male.

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Our subjects were 70 patients undergoing maintenance hemodialysis (HD) in a single facility. The generation of factors in the infected animals that inhibit the autologous activity of complement as the infection goes on reduces the risk of complement-mediated tissue damage and prolongs the survival time of the host, a wise strategy on the part of the MLM to assure its own survival as a parasite. Diclofenac prevents temporal increase of intraocular pressure after uneventful cataract surgery with longer operation time. By creating a magnetic field gradient in the vicinity of the substrate, well-defined forces were applied on these magnetic aggregates which in turn induced a deflection of the micropillars.

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There is some evidence that early pharmacological intervention with antiestrogens may diminish persistent pubertal gynecomastia, but treatment with an aromatase inhibitor has not been shown to be more effective than placebo. These perspectives (life sciences, social and environmental) are all required if policy engagement and clarification is to occur.

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The interactive presentation of 3D information obtained from reconstructed datasets and 3D placement of single histological sections with the 3D portable document format. The NK cells were treated with vitamin E or beta-carotene while target cells were labeled with sodium 51chromate. We report on a 28 year old man who developed an isolated tuberculous liver abscess not associated with lung involvement.

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Acid phosphatase was localized on day 1 in mvb and bdb in both cell types, indicating that these structures are lysosomes. The role and mechanism of action of 13-cis-retinoic acid in the treatment of severe (nodulocystic) acne. Worldwide malaria risk due to Plasmodium vivax makes development of vaccine against P.

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To pool results from studies of patients with hypertrophic cardiomyopathy (HCM) to elucidate important phenotypic differences among genotypes. The role of Cat1 overproduction in virulence and colonization was also analyzed in mouse models.

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Most teams do not use formal measures in their assessment of psychological concerns, and they provide feedback via discussions with the families. Nitrite is currently recognized as a biomarker of the state of nitric oxide metabolism.

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Good superimposition of the images was found, which seems important in neoplastic invasion of the infratemporal fossa and which may lead to a pathogenic interpretation of the algo-dysfunctional syndrome of the masticatory apparatus. Why no consensus prognostic classification for hepatocellular carcinoma? We investigated the clinical significance of serum galectin-3 levels in SSc. Presumably, toluene suppresses the immunity starting from the second week after treatment. To systematically search for studies reporting outcomes for adenoidectomy alone as a treatment for paediatric obstructive sleep apnoea and use the data to perform a meta-analysis.

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The complication and morbidity rates were extremely low, while the mortality rate was zero. AIM To investigate the effect of mild, moderate and severe liver impairment on the pharmacokinetics (PK), tolerability and safety of clazosentan, an intravenous endothelin receptor antagonist. This agent also caused respiratory depression, hypotension and the relief of decerebrate rigidity. The complex deformity of both forearm bones is difficult to assess on plain radiographs or cross-sectional images. In addition, RECP results were validated by testing 47 field samples from different sources and by sequencing of their RT-PCR products.

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Home-based, self-directed interventions may be of particular service to veterans who are distant from, averse to, or prohibited by schedule from using professional services. A 45-years old man after having returned from Thailand was admitted to the hospital with a severe ulcerative, pyogenic colitis and multiple liver abscesses. Photofragmentation of the K-shell excited perfluorocyclobutane: anisotropies in the fragments and breakdown pathways.

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A total of 15 patients with locally aggressive bone tumors (Enneking stage II) in the adjacent muscle (tendon) insertion of the proximal extremity were enrolled in the present study (mean age of 29 years). In this paper the adsorption and desorption of carbon monoxide on the stepped Rh(553) surface decorated with Ni is reported.

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Within the Trichonymphida, the most diverse lineage of hypermastigote parabasalids, molecular data are now available from five of the six families, however, one family, the Spirotrichosomidae, has not been sampled at the molecular level, and is very little studied with electron microscopy. The clinical and pathological features suggest that excessive glucose storage by the tumor is an important factor in the pathogenesis of the hypoglycemia. Our experience confirms the advantage of a staged reduction in giant gastroschisis.

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This was followed by gentle retraction of the hernial content into the abdominal cavity and performing a standard transabdominal preperitoneal (TAPP) repair. C32S did not inhibit thioredoxin reductase, apparently due to aggregation of the oxidized C32S species. In cells exposed to OGD, inhibition of TRPM8 and cAMP-PKA signaling suppressed the expressio of UCP4 and increased the cell apoptosis.