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Concentration- and time-dependent cytostatic effects of methotrexate and etoposide on L1210 leukemic cells in vitro demonstrated by a new microperfusion method. Resolution of Conflicting Signals at the Single-Cell Level in the Regulation of Cyanobacterial Photosynthesis and Nitrogen Fixation.

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Administration of LPS caused a decrease in mean blood pressure and an increase in heart rate. Transactive response DNA-binding protein (TARDBP/TDP-43), a heterogeneous nuclear ribonucleoprotein (hnRNP) with diverse activities, is a common denominator in several neurodegenerative disorders, including amyotrophic lateral sclerosis and frontotemporal lobar degeneration. These data provide evidence of a key role for genetic factors in determining the host response to filarial infections in humans and emphasize the complexity of the relationships among the host, parasite, and environment. We also searched clinical trials databases, conference proceedings and the reference lists of retrieved articles for randomised controlled trials and quasi-randomised trials. To assess the general knowledge of HIV/AIDS, its oral manifestations and willingness to know more about its oral lesions among people living with HIV/AIDS (PLWHA) in Lagos, Nigeria.

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Costs and effectiveness of angiotensin converting enzyme inhibition in patients with congestive heart failure. A modified mammalian one-hybrid assay showed that the NH(2)-terminal proline-rich domain of Zimp7 and the region spanning amino acids 321-486 of PIAS3 were the primary interaction segments. Significance of determining the antithrombogenic properties of the vascular wall in the prevention of thromboses Oxidative stress, defined as an imbalance between the production of reactive oxygen species and antioxidant defense, is considered to be an important pathogenic factor in leukemia-prone bone marrow diseases such as FA. This requires an improved evidence base on the effects of national and international policies on health inequities.

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Regulation of CXCR4 conformation by the small GTPase Rac1: implications for HIV infection. Microalbuminuria may predict proteinuria and increased mortality in non-insulin dependent diabetic patients. All nerves to the hind paw were cut and tied to prevent regrowth. The present contribution examines in greater detail how the symmetry of the ligand field surrounding the metal ion can be probed using these X-ray techniques. Chikungunya fever struck the Andaman and Nicobar Islands in July 2006.

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Osborne described several case studies involving wood smoke exposure to children, with emphasis on the significantly greater occurrence of chronic respiratory symptoms and acute chest illness for children from homes heated with woodburning stoves.(ABSTRACT TRUNCATED AT 250 WORDS) Impaired contralateral kidney (CLK) function is important in the maintenance of hypertension in the two-kidney, one-clip (2K, 1C) Goldblatt rat model. This technique can be used to read and write ferroelectric field-induced regions with a size as low as 20 nm.

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In 1988, a less invasive, low-cost procedure, laparoscopic cholecystectomy (LC), was introduced and became the standard of care for management of gallstones. In this study we analyzed 44 metastatic melanoma samples with a known BRAF(V600E) mutation status with immunohistochemical expression of the BRAF(V600E) protein. Data from a sample of over 100 youth ages 7 to 17 with a primary DSM-IV diagnosis of OCD support the use of the 21-item OCI-CV. The impact of changing diagnostic criteria in posttraumatic stress disorder in a Canadian epidemiologic sample.

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Effect of chronic treatment with ladostigil (TV-3326) on anxiogenic and depressive-like behaviour and on activity of the hypothalamic-pituitary-adrenal axis in male and female prenatally stressed rats. Here, we proposed to evaluate the potential use of Brachyury protein expression as a new prognostic biomarker in gastrointestinal stromal tumors (GIST). Of them there were 24 saddle nose, 4 auricle defects, 6 secondary deformities of cheiloschisis, 4 mandible deformities. Consistent with this hypothesis, considerable amplification of wild-type BPV-1 DNA associated with characteristic giant cell formation was observed in typical wild-type virus-transformed C127 cultures following a period of growth arrest achieved by serum deprivation.

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Thus, this study examined the interactive effects of the intensive control of all 3 conditions on the progression of renal function. The detailed behavior of circular bend attenuation in GaAs/AlGaAs rib waveguides is explored both experimentally and theoretically. CD44v3 isoforms may be effective tumor markers and targets for HNSCC therapy. Thus, accelerated size-specific growth without hyperphagia restored body condition but not size. This fact has lead to a conclusion on the contribution of mycoses of the soles to sensitization of the body to industrial allergens.

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Report of the XXIX meeting of the Pan American Health Organization Advisory Committee on Health Research (ACHR). Finally, we showed that the induction of Sestrin-2 by Sevoflurane was mediated by p53.

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The mechanism of death was hemorrhagic hypovolemic shock due to renal hemorrhage complications due to ESWL for treatment of renal calculi. This differential susceptibility could have broader consequences for grub management if a numerically dominant target species is more completely suppressed than a co-occurring species. Therefore, the surface profiles of citrate synthase enzymes from yeast, pig, rat, tomato and Escherichia coli were investigated with immunological methods using monoclonal antibody families generated against either pig citrate synthase (alpha-PCS) or yeast citrate synthase-2 (alpha-YCS-2).

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We hypothesize that conformational partitioning and fluctuations in protein ionization at alkali pH play an essential role in the appearance of fluorescent properties of KFP. In an economically disadvantaged environment, the re-operation rate after an abdominal surgery does not seem to be higher than that seen in series from developed countries, although there may be factors which bias this observation. The hybrid transgene approach was adapted to study the physiological pathway(s) in which the p53 suppressor gene is involved.

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Further study is needed for comprehensive understanding of the contextual factors of microbicide use. Wen of Hong Kong was the first (1972) to report that acupuncture at 4 body points and 2 ear points combined with electrical stimulation can relieve opioid withdrawal signs in the addicts. TNF-alpha signaling is not required for in vivo transcriptional reactivation of latent murine cytomegalovirus.

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Two low-pathogenicity (LP) and two high-pathogenicity (HP) avian influenza (AI) viruses were inoculated into chickens by the intranasal route to determine the presence of the AI virus in breast and thigh meat as well as any potential role that meat could fill as a transmission vehicle. Standard acrylic resin tray samples of 1-inch square surface were made. Nuclear-cortical interaction tests are highly significant, indicating that nuclear sclerosis and cortical opacities have opposite effects on the relative risk of senile maculopathy. Thymocyte LAK precursors are of low to medium density, CD1-negative, and predominantly CD3-negative.

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The conclusions in this report apply specifically to regions where malaria is endemic. Human mesenchymal stem cells (hMSCs) were cultured in hydrogels in vitro for 10 days to induce neuronal differentiation of hMSCs. Toluidine blue and Mallory staining analysis revealed the localized deposition of mineralized bone-dentin matrix that was detected at the site of dental pulp cells. Also enzymes from anaerobes do not seem to be a particularly closely related group and are not more closely related to each other than to enzymes from aerobes. In contrast, group mean core temperature was unchanged in those with autonomic neuropathy and fell in 3 subjects (P less than .001).

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This effect appears within several studies during the whole period of amoxapine administration (3 or 4 weeks). Specific amplification of the human H1t gene using template DNA samples from a NIGMS human/rodent somatic cell hybrid mapping panel has shown that the human histone H1t gene is located on chromosome 6. Here, using BOLD-fMRI, we compared retrieval of semantic associations acquired through Fast Mapping (FM), an incidental, exclusion-based learning procedure, to retrieval of similar associations that were intentionally acquired through Explicit Encoding (EE).

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The nucleotide sequence and the amino acid sequence of this CGTase (CGTase 17-1) gene had strong homology with those of the CGTase (CGTase 38-2) gene previously cloned in our laboratory from the alkalophilic Bacillus sp. We observed that experience (determined by letter frequency) affected the access to iconic memory but not the temporal decay constant. Functional avidin levels of 1.54 microM (26.1 microg/g leaf tissue) were detected in tobacco leaves expressing vacuole-targeted avidin. Penetrating thoracic injuries can damage more than one intrathoracic structure and frequently require urgent surgical intervention due to life-threatening consequences. The receptors protein levels increased from the early days to the advanced days of gestation, but this alteration was not significant.

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Making the business case for hospital information systems--a Kaiser Permanente investment decision. The problem of steering such instruments, however, remains a challenge, because no study investigated which control method is the most suitable.

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The long-term effectiveness of psychoanalytic psychotherapy for young adults was supported. We studied 22 patients undergoing liver resection for metastases from neuroendocrine tumors between 1997 and 2007.

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Thereafter, she received regular hormone therapy and had generally felt well. Patients who have a pineal germinoma usually present with symptoms of intracranial hypertension or disturbances in vertical ocular motion but rarely present with amnesia.

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From animal models to human genetics: research on the induction and pathogenicity of autoantibodies. It is more of a focus on the feelings of others rather than on our own.

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Survey respondents may inaccurately report mental health service utilization for motivational and cognitive reasons. Action of prodigiozan on the embryonic development of experimental animals

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SOC is a predictor of mental and physical HRQoL at 12-28-month follow-up, crude and also after adjustment. The binding free energy values obtained for E67Q were found to be comparable to those previously obtained in liquid phase, but less dependent upon the chain length of the oligosaccharides.

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The patient was managed expectantly, with resolution of the liver disease and delivery five weeks after discharge. This article describes the diagnosis, assessment and management of anxiety disorders in the general practice setting.

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Estimating separately personal exposure to ambient and nonambient particulate matter for epidemiology and risk assessment: why and how. Potassium currents contributing to action potential repolarization in dissociated cultured rat superior cervical sympathetic neurones.

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None of the five patients developed postoperative blepharoptosis, and all had excellent functional and cosmetic results. We consider the problem of estimating the mean hospital cost of stays of a class of patients (e.g., a diagnosis-related group) as a function of patient characteristics. EUS imaging had a low accuracy rate in the diagnosis of gastric subepithelial lesions, and endoscopic submucosal resection should be performed to provide a histologic diagnosis. Characterization of vascular dopamine receptors in the gastric circulation of the rabbit.

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Each subgroup consisted of 4 animals, and the tibias were extracted and removal torque was measured. And when cultured under serum-containing condition, none of them showed GR silence anymore. Estimation of the size of lipoprotein particles with Lipoprint method among newly diagnosed, untreated patients with these patients have not been evaluated yet. Patient monitoring in the intensive care unit typically relies upon central venous pressure devices, whereas the primary focus in the operating theater is blood volume deficit estimated from suction devices. The number of alleles labeled at each locus and the number of labeled different and repeating alleles at each locus as well over all loci for 2 HT-DNA or 3 LT-DNA replicates were determined.

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Respiration-correlated image guidance is the most important radiotherapy motion management strategy for most lung cancer patients. Pilot study of 1650-G: a simplified cellular vaccine for lung cancer. The data set can be used to verify a biomechanical model adjusted to the individual characteristics by a comparison of measured and predicted intradiscal pressures. Mice deficient in one or both of these isoforms are viable and fertile but exhibit profound functional, metabolic and structural muscle remodelling that primarily affects fast skeletal muscles, which show an increased contribution of oxidative metabolism to contractile function.

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Ranitidine in the prevention of upper gastrointestinal tract hemorrhage following thermal injury The model was also used for intravital imaging of spinal micrometastases resulting from primary brain tumor using fluorescence and bioluminescence imaging.

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We discuss other photonics applications of the crystal quartz WGM resonators in narrowband agile tunable filters, compact narrow linewidth lasers, and microwave and millimeter wave oscillators. A fuzzy model was developed to measure distress levels in cosmetic surgery patients based on the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), diagnostic criterion B for BDD. The effect of uridine diphosphate glucuronosyltransferase (UGT)1A6 genetic polymorphism on valproic acid pharmacokinetics in Indian patients with epilepsy: a pharmacogenetic approach. The antiviral potential of Mx2 protein remains unknown, because the Mx2 gene in commonly used strains of laboratory mice is nonfunctional.

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Our results demonstrated that the needle can be left in situ for the entire time the patient is at home between cycles of chemotherapy. It can be single or multiple, solitary piloleiomyoma are common over genitalia.

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Magnetotactic bacteria (MTB) can rapidly relocate to optimal habitats by magneto-aerotaxis. Future research needs to determine whether additional culturally appropriate modifications of the SDM would increase its usefulness for Mexican American adolescents. The initial diagnosis of the aortic dilatation was made by ultrasonography and, after the surgical treatment was indicated, the patient was submitted to another imaging method. This article reviews the results of ten recent studies of the meningococcal proteome and compares the different methodologies employed. Our findings do not support special consideration of bacteremia in imaging decisions for otherwise well-appearing young infants with UTI.

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Coal, firewood and cigarette smoke were important sources of carcinogenic and kerosene and gas were sources of non carcinogenic polycyclic aromatic hydrocarbons. Clinical features, outcomes and predictors of in-hospital mortality. One advantage of this procedure is that placement of an implant-supported prosthesis or other form of prosthetic tooth replacement is not needed.

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Immature or degenerated taste bud-like structures in the larynx were assumed to be mechanical receptors because these receptors lacked outer taste pores and taste hairs. Plant CLAVATA3/ESR-related (CLE) peptides have diverse roles in plant growth and development. It is regarded as the reference method for detection of esophageal motility disturbances but, up to date, performance of the procedure is not standardized among centers.

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The bulk of pharmacogenomic research has focused on the role of single nucleotide polymorphisms, copy number variations or differences in gene expression levels of drug metabolizing or transporting genes and drug targets. To elucidate the role of succinic semialdehyde (SSA), gamma-hydroxybutyrate (GHB) and GABA in the accumulation of ROIs, we combined two genetic approaches to suppress the severe phenotype of ssadh mutants.

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Little is known about drug hypersensitivity reactions from antituberculosis drugs. In high doses or concentrations it suppresses myocardial contraction and ventricular automaticity, nearly sparing sinoatrial nodal automaticity and atrioventricular nodal conduction. SMI is a detergent-binding glycoprotein of 58 to 90 kDa found at several stations along the endocytic path: in coated pits, coated vesicles, endocytic vesicles, but not in lysosomes. We analyzed true lateral radiographs of children and adolescents with MRI-detected trochlear dysplasia. Clinical research in ophthalmology benefits particularly from an outpatient diagnostic index.

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difficile can be found in faecal samples obtained from pigs after they were stunned and bled in a slaughterhouse. Therefore, ALCAR was targeted as a possible pharmacologic intervention to prevent, or even restore, hearing loss from aging. Following these domains, the short product has 12 tandem EGF-like repeats, whereas the long product has approximately 20 tandem repeats. Colonoscopy in patients with suspected inflammatory intestinal diseases Highly immunogenic regressor tumor cells can prevent development of postsurgical tumor immunity.

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This method of visualizing catheter placement may not be ideal for patients who are pregnant. The characterization of patients with inherited mutations in selenoprotein N has corroborated the physiological importance of selenium for muscle function. The purpose of this paper is to present a study of how quality improvement tools and techniques are framed within healthcare settings.