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Microvillous localization of cathepsin E was found in the intracellular canaliculi of human and rat gastric parietal cells, rat renal proximal tubule cells, and the bile canaliculi of rat hepatic cells. The MIC90 reached the critical value for cefotaxime in the case of Citrobacter spp., Escherichia coli, Klebsiella spp., Proteus mirabilis, Salmonella spp. There is substantial experimental and pre-clinical evidence showing that the S protein is a promising lead for vaccines and therapeutics. A force-length-time relationship describes the mechanics of canine left ventricular wall segments during auxotonic contractions.

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Algorithm for probable acute coronary syndrome using high-sensitivity troponin T assay vs fourth-generation troponin T assay. The computer-aided holographic interferometer was tested using disk-shaped acrylic resin materials.

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Introduction: relations between traditional and modern medical systems. A screening, prevention, and restoration model for saving the injured brain in intensive care unit survivors.

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For a given image, a classifier builds a saliency map online and uses it to classify the image. Advancing knowledge in this may lead to better control and prevention of genetic diseases. Use of a hybrid optical spectrometer for the measurement of changes in oxidized cytochrome c oxidase concentration and tissue scattering during functional activation. In autoimmune disorders there is usually only one cell-type involved but occasionally there are more.

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Facilitating emergent literacy: efficacy of a model that partners speech-language pathologists and educators. The enzyme monoamine oxidase was labelled in the rat striatum or substantia nigra with locally injected radioactive pargyline. Statistical analyses compared percentage of subjects with no heartburn 24 h after the first dose, after the last dose (day 14), and percentage of days that subjects were heartburn-free. Survival of patients undergoing TAVI was also compared with that of a population undergoing surgical aortic valve replacement. To examine the clinical and radiographic appearance of teeth with immature apices that were treated by single step procedure using mineral trioxide aggregate (MTA).

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The left cerebral hemisphere appeared to enjoy a better blood supply. Etiology of diarrhea among travelers and foreign residents in Nepal.

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Here, we show that RasL11a is a chromatin-associated modulator of pre-ribosomal RNA (pre-rRNA) synthesis. Other, more common causes of neurologic abnormalities in foals, such as trauma, vertebral body abscesses, brain abscesses, and meningitis, must be ruled out before portosystemic shunt is considered. The dependence of the Fas concentration in the liver tissue and serum was estimated in reference to the elimination of HBV-DNA, necroinflammatory changes and fibrotic activity in chronic hepatitis B patients treated with lamivudine. Compared with when alone, birds cached less in the noisy substrate when with a conspecific that could hear but could not see them caching. The congenital disorders of glycosylation (CDGs) are progressive multisystemic disorders characterized by a heterogeneous deficiency of the carbohydrate moieties in various structural and circulating glycoproteins, representing a natural model for glycoprotein hormone studies.

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The conformation of a transmembrane peptide, sMTM7, encompassing the cytoplasmic hemi-channel domain of the seventh transmembrane section of subunit a from V-ATPase from Saccharomyces cerevisiae solubilized in SDS solutions was studied by circular dichroism (CD) spectroscopy and fluorescence spectroscopy of the single tryptophan residue of this peptide. Viral shedding after p53 adenoviral gene therapy in 10 cases of esophageal cancer. The analysis of hospital morbidity data using life table methods.

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With neurons as a model system, a critical review of these regulatory mechanisms is presented here, with a particular focus on the emerging contribution of compartmentalised MAPs. Single-center reports have identified retrograde ascending aortic dissection (rAAD) as a potentially lethal complication of thoracic endovascular aortic repair (TEVAR).

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Treatment of prevesical ureteral calculi by extracorporeal shock wave lithotripsy. Behavioral and histological studies were performed on a reversible ischemia model in rats. This implantation approach allows (1) a prospective double-blind investigation of the effects of PSA stimulation compared to baseline, as well as (2) a crossover comparison between VIM and PSA stimulation with respect to tremor suppression and side effect profiles. In the present study, we determined whether phorbol esters alter contraction by augmenting calcium influx through calcium channels.

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The vasopressor/constrictor response to vasopressin was not influenced by bilateral adrenalectomy, reserpine pretreatment or the prior administration of the alpha-adrenoceptor antagonists prazosin and yohimbine. Many small molecules were shown to diffuse through the D1 channel in the proteoliposomes, and the permeation rates of D-glucose, L-glucose, D-xylose, and L-xylose were much higher than expected for their size. Newer oral anticoagulants such as rivaroxaban and dabigatran offer alternative therapeutic options for the extreme elderly. Multiplexed immunoassay for the rapid detection of anti-tumor-associated antigens antibodies. Moreover, Klotho overexpression increased cellular migration, anchorage-independent growth, and anoikis resistance in hepatoma cells.

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The diagnosis of DLBCL was based on the criteria established by the WHO classification. Massage administered 30 minutes after exercises could have a beneficial influence on DOMS but without influence on muscle swelling and range of motion. To evaluate the properties of solidifying volatile oil with graphene oxide, clove oil and zedoary turmeric oil were solidified by graphene oxide.

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These results indicate that regional arterial infusion of anticancer drugs combined with direct hemoperfusion would be useful for preventing their toxicity. The aim of this study was to compare the outcomes of surgical treatment of osteomyelitis caused by methicillin-resistant Staphylococcus aureus (MRSA) with cases caused by methicillin-sensitive Staphylococcus aureus (MSSA). After 30-60 min of hypotonic treatment the recovery of microtubules and the thickening of intermediate filaments around the nucleus are observed, which promotes a disguise of intermediate organizing centres. Morphological alteration and increased tyrosine phosphorylation of 130-140 kDa proteins, the major component of which is the Crk-associated p130, were observed in cells expressing B-Crk as well as those expressing v-Crk, but little in cells expressing c-Crk even at a similar level of expression. Neurogenesis in the developing visual system of the branchiopod crustacean Triops longicaudatus (LeConte, 1846): corresponding patterns of compound-eye formation in Crustacea and Insecta?

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We report a technique for umbilical single-port liver cyst fenestration combined with cholecystectomy using only standard and reusable laparoscopic instruments. Plasma kinetics of tritiated d-alpha-tocopherol in sheep given intravenously in emulsion or ethanol.

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DNA degradation in the terminus region of resolvase mutants of Escherichia coli, and suppression of this degradation and the Dif phenotype by recD. 11 proteins are essential for the disease-causing bloodstream form of T. Our results showed that the cold induced expression of CBF9 and CBF14 transcription factors is regulated by phospholipase C, phospholipase D pathways and calcium. The finding of mutations of KIT in gastrointestinal stromal tumors (GISTs) and subsequent development of kinase-directed therapy in metastatic GIST serve as a touchstone for the translation of laboratory research into clinical therapeutics. Fetuses of diet-reversal mothers had normal melanocortin levels.

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Studies using RIP-Cre:Vegf(fl/fl) mice revealed that defects in the normal vascular structure are associated with abnormal insulin secretion and concluded that the islet vascular system is essential for normal insulin secretion into the blood stream. Early recognition of the disorder and prompt use of corticosteroids and vaginal dilators may prevent the common sequelae of adhesion formation and vaginal stenosis. Two readers independently reviewed the baseline ultrasound (BUS) and CEUS images and the diagnostic performances were evaluated by receiver operating characteristic (ROC) analysis. Comparison of excitation energy transfer in cyanobacterial photosystem I in solution and immobilized on conducting glass.

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Unlike conventional inference methods which usually rely on asymptotic arguments, Bayesian inferences are valid in arbitrary sample sizes, and thus the method is ideal for the study of rare or endangered species for which small data sets are typical. This result compared extremely well with an independent determination using centrifugal disc photosedimentation (CDS), thus validating the method. Popliteal artery entrapment syndrome (angiographic finding in one case report). Additionally, the proband and two of his children had decreased Hageman factor (factor XII) levels consistent with those of heterozygous carriers of Hageman trait.

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This store of functional sequences could be maintained at almost no selective cost. Subjective determination of the most lifelike porcelain depended on the shade.

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Acetylcholinesterase density and turnover number at frog neuromuscular junctions, with modeling of their role in synaptic function. Killing of bacteria with electric pulses of high field strength. The goal of the project was to establish a fully integrated automated synthesis solution that was initially focused on minimizing the burden of repetitive, routine, rules-based operations that characterize more established chemistry workflows. Leaders described current signs of change within mental health settings and expressed optimism about the possibility to lower future rates of smoking among mental health consumers and staff members.

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The overall incidence of DGF was high and similar to that in previously published reports, but more common in women. Effects of erlong zuoci pills and its effective disassembled prescriptions on gentamycin induced hair cell apoptosis Tripotassium dicitrato bismuthate showed no inhibition of the proteolytic activity of either the pure porcine or the human pepsin in the gastric juice.

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Preliminary results of N-glycan analysis for several other glycoproteins under these conditions are also presented. Repeated exposure of goldfish (Carassius auratus) to tricaine methanesulfonate (MS-222). In blunt abdominal trauma patients, operations to establish diagnosis do not add significantly to complication burden. Distribution of chloramphenicol in the genital tract of postpartum cows. Spatial differences in active caspase-8 defines its role in T-cell activation versus cell death.

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Improved processing of susceptibility-weighted MR phase images offers a new means of contrast for neuroimaging applications. ERP studies of emotional stimulus processing frequently report differential responses to emotional stimuli starting around 120 msec. Reproductive and family planning history, knowledge, and needs: a community survey of low-income women in Beijing, China.

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Effect of nitric oxide on megakaryocyte growth induced by thrombopoietin. Although outcomes are poorer with AKI than with normal renal function, they are better than those found in other intensive therapy unit populations. Effect of antitumor lichen-glucans and related derivatives on the phagocytic activity of the reticuloendothelial system in mice. The prosomal RNA-binding protein p27K is a member of the alpha-type human prosomal gene family. With the addition of DTT or GSH, the entrapped drug released quickly due to the cleavage of the disulfide bond.

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Comparable sustained virologic response (SVR) rates have been documented between Asian patients who received 24 weeks of pegylated interferon (IFN) plus ribavirin and white patients who received 48 weeks of combination therapy for hepatitis C virus genotype 1 (HCV-1) infection. Neuronal activity, ATP generation, blood flow, oxygen consumption, glucose utilization, and mitochondrial oxidative metabolism are all interrelated.

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Analgesia induced by N-acetylserotonin in the central nervous system. Synthesis, characterization, and cytotoxicity studies of a novel palladium(II) complex and evaluation of DNA-binding aspects.

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Effect of the hypothalamic stimulation on the potential difference in the toad skin in situ. Incorporating palliative care into undergraduate curricula: lessons for curriculum development. On the other hand, cysteine could not scavenge the radicals efficiently in a lipid region. The objective response rate is insufficient to justify wide clinical application. Expression quantitative trait loci detected in cell lines are often present in primary tissues.

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No effect of exercise on insulin-like growth factor 1 and insulin-like growth factor binding protein 3 in postmenopausal women: a 12-month randomized clinical trial. Patients with a positive DWI lesion were compared to those with negative DWI findings on demographics, risk factor profile, final discharge diagnoses, and outcome. Imaging integration is a new technology that enables guidance during this procedure by showing a three-dimensional, pre-acquired computed tomography or magnetic resonance image and the relative real-time position of the ablation catheter on the screen of the electroanatomic system.

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Traumatic giant pseudoaneurysm of the middle meningeal artery causing intracerebral hematoma. The numbers of motoneurones surviving after metamorphosis were almost normal on both sides provided the operation was done before motor invasion of the limb bud begins. Low level postnatal methylmercury exposure in vivo alters developmental forms of short-term synaptic plasticity in the visual cortex of rat.

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The E3 ubiquitin ligase RNF135 regulates the tumorigenesis activity of tongue cancer SCC25 cells. Well differentiated human hepatoma cells may respond differently to different cytokines.

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For the determination of the distribution of these glycolipids in various nervous tissues and, thereby, the elucidation of their pathogenicity, a quantitative immunostaining-TLC method for their detection has been devised. Although a golden time to relocation cannot be fully established from this study, early relocation is advised to decrease the potential risk of vascular spasm, scarring, and subsequent avascular necrosis. A conserved open reading frame that overlaps the herpes simplex virus thymidine kinase gene is important for viral growth in cell culture. In breast cancers, the expression, or lack thereof, of E-cadherin can differentiate tumor types, whereas the misexpression of either P-cadherin or N-cadherin can be a marker of poor prognosis or increased malignancy, respectively.

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In general, it was found that ultrasound irradiations enable some reactions to occur which could not be carried out under silent condition in addition to improvement in reaction times. The blink reflex in chronic tension-type headache, migraine, and cervicogenic headache. Beyond moral outrage--weighing the trade-offs of COI regulation.

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There are unique aspects of antimicrobial use in elderly persons that make prescribing complicated and monitoring unpredictable. Otago Glaucoma Surgery Outcome Study: cytology and immunohistochemistry of trabeculectomy blebs. This favours introduction of PA in the treatment of RA patients. Iatrogenic intradural spinal arachnoid cyst as a complication of lumbar spine surgery.

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In this respect, defining patients according to their initial response profiles was shown to have great impact on choosing the optimal treatment duration. Binding of PBL to CD48 transfectants was almost totally inhibited by either CD48 mAb pretreatment of COS cells or CD2 mAb pretreatment of PBL, implying an interaction between CD2 and CD48. A rare case is reported of a fistula between the left internal iliac artery and the left ureter in a patient whose left kidney was the only functioning kidney. Specifically, under conditions where aptamer-ligand binding induced a conformational change from a relaxed random coil to more intricate secondary structures (e.g., double helix, G-quadruplex), a transition from planar to homeotropic LC orientation was observed. Although a DNA 2 component is unique to whitefly-transmitted geminiviruses, the results demonstrate that neither coding region is involved solely in insect transmission.

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Failure was defined as nonhealing of the surgical wound or fistula. Comparative studies with MRI, SPECT, and CT in patients with epilepsy of unknown origin. K-shell x-ray emission enhancement via self-guided propagation of intense laser pulses in Ar clusters.

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Monitoring of beta-galactosidase activity suggests the influence of catabolic repression on malT transcription, sincethe activity of malT promoter was decreased twofold in the presence of glucose. Exposure of EGF-synchronized BALB/MK cells to high levels of calcium was associated with a striking decrease in the early burst of c-fos RNA as well as the subsequent peak of cell DNA synthesis. This chemical similarity validates their common application in the pharmaceutical industry as anti-CHD herbal drugs. Epithelial salivary tumor was rare, parotid gland was most common involved site, pleomorphic adenoma and mucoepidermoid carcinoma were the most common benign and malignant tumor respectively. Correlation between polymorphism of platelet alloantigen genes HPA-1-5 and type 2 diabetes complication by carotid atherosclerosis in a Chinese population.

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In order to study the effect of heterocyclic core conformational state of leucamide A on its anti-influenza virus A activity, five conformational analogues were prepared by replacing the Pro-Leu dipeptide in the molecule with various amino acids. Running decreases knee intra-articular cytokine and cartilage oligomeric matrix concentrations: a pilot study. The 274C/T SCL11A1 polymorphism was found to be associated with T1DM as well as the presence of MAP DNA in blood. The proportion of such pregnancies identified by a risk scoring system can be increased by choosing a more lenient threshold criterion for the score beyond which the pregnancy is regarded as being at risk. Other findings included a compounding of discrimination for ethnic minority women, the unique resource problems faced in rural contexts, and the difficulties that attend access to shelter and housing for parents with SMI.

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Because of this, hepcidin may become a useful tool for diagnosis and management of iron disorders. Previously, macrophage stimulating protein (MSP)-a serum protein mainly secreted by liver-was shown to inhibit oxidized low-density lipoprotein (OxLDL)/lipopolysaccharides (LPS)-induced inflammation in mouse macrophages.

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Inequities in maternal postnatal visits among public and private patients: 2004 Pelotas cohort study. The nChE staining of Schwann-derived structures surrounding sensory terminals allowed us to identify unequivocally the sensory corpuscles in the skin and the muscle proprioceptors (muscle spindles and Golgi tendon organs) in longitudinal sections of muscle tissue. Such nutrients were lost into the imbibition medium at the expense of suitable mobilization to the growing embryonic axis. It was used the common questionnaire survey Pediatric Quality of Life Inventory (PedsQLtm4.

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Fine structure of the pheromone-sensitive sensilla on the antenna of the hawkmoth, Manduca sexta. Prospective study of chronic disabling occupational lumbar disorder (CDOLD) patients completing a functional restoration program. Chaos and regular dynamics in model multi-habitat plankton-fish communities. Escape mechanisms of melanoma from immune system by soluble melanoma antigen.

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High HDL-C levels in elderly individuals may be associated with a decreased risk of AD. The average initiation mass was determined by two methods: (i) from a mathematical relationship between average cell mass, cell age at initiation and number of origins present in the cells, and (ii) directly from the cell mass distribution. Consolidation of board examinations may be in the best interest of physician nutritionists. Tolerance of pool therapy by ankylosing spondylitis patients with low vital capacities.

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BioS has been structured as a flexible, modular, and portable environment. Nonalcoholic fatty liver disease (NAFLD) is associated with inflammation and increased risk of atherosclerosis. This new molecular insight could have a crucial impact on diagnosis and also on improving and selecting an appropriate treatment to the patients with thyroid malignancies. Efficacy, safety and tolerability of tocilizumab in patients with systemic juvenile idiopathic arthritis.

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In the derivatization and extraction procedure, 2,4-dinitrophenylhydrazine (DNPH) as derivatization reagent and formic acid as catalyzer were injected into the sample solution for derivatization with aldehydes, then the formed hydrazones was rapidly extracted by dispersive liquid-liquid microextraction with 1-dodecanol as extraction solvent. Glioma grade is associated with the accumulation and activity of cells bearing M2 monocyte markers. We used Cox proportional hazards models to explore gender differences in CRP-associated mortality via the National Health and Nutrition Examination Survey III 1988-1994 linked to the National Death Index with mortality follow-up through 2006.