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We discuss a model of cooperative and non-cooperative cell-to-cell communication that can capture the interplay between cellular competition and tissue dynamics. Here, we exemplify at the hand of the exactly solvable Jaynes-Cummings (JC) model and its generalization to finite JC lattices that finite component systems of coupled spins and bosons may exhibit quantum phase transitions (QPTs). Bilateral total knee arthroplasty (BTKA) can be performed sequentially during one anesthetic. The effects of matching for HLA-A and -B did not reach statistical significance. Data were retrospectively extracted from a formal multicentre clinical trial, which was originally designed to evaluate the safety and efficacy of cyclosporin dose reduction and cyclosporin elimination in patients receiving sirolimus.

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Although the recommendation to avoid animal flesh for environmental reasons has been increasingly advanced, especially in the highly industrialized countries, the ecological implications of such avoidance are seldom carefully examined. The redox enzyme glucose oxidase from Aspergillus niger was displayed on the surface of Saccharomyces cerevisiae using the Yeast Surface Display System in a high copy number and as an active enzyme. The recent development of lentivirus vectors for transgene delivery may overcome some of this limitation. The present case, an incidental finding at autopsy, is the third case of schwannoma of the trochlear nerve and the first to illustrate the morphological relationship between this tumor and nerve.

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Recent studies showed that generation of double-strand DNA breaks at specific loci by designed endonucleases greatly increases the rate of homology-directed gene repair. Mutational analyses revealed that amino acid at HA position 190 (H3 numbering) primarily determined the specificity of receptor binding, while the insertion at position 133 influenced the avidity of receptor binding. Stasis is thought to play a key role in the development of gallbladder sludge and gallstone formation.

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The LH-RH test usually was normal in patients with hypothalamic syndrome, following loss of weight, but it was pathological in almost all cases of nervous anorexia, depending on the amount of weight loss. Uniportal video-assisted thoracoscopic lobectomy: two years of experience. Although many analyses of S-1 side effects are reported, there are no reports where the analyses of side effects were performed in consideration of renal function, which is an important index of medication dose. We have created high-resolution x-ray imaging devices using polycrystalline mercuric iodide (HgI(2)) films grown directly onto CMOS readout chips using a thermal vapor transport process.

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Associative effects between two fibre sources on ileal and overall digestibilities of amino acids, energy and cell-wall components in growing pigs. It is an independent, strong predictor of morbidity and mortality.

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Our results allow discriminating three types of emitters differing in positions of their excitation and emission bands. A dose-dependent protective effect was observed with all doses of eugenol and N-acetylcysteine, as evidenced by decreased level of superoxide anion generation and malondialdehyde, and also increased level of reduced glutathione, and superoxide dismutase activity. Increased circulating concentrations of asymmetric dimethylarginine (ADMA) in white coat hypertension. We suggest that arousal produced by both PSD and PSD procedures could have improved the acquisition of the conditioning, whereas PSD per se could have been detrimental for LTR of the learned response.

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Using surfactant protein C (SP-C) as a marker, we previously showed that stretch-induced fetal type II cell differentiation is mediated via the ERK pathway. One of the most important features of the nasal route is that it avoids first-pass hepatic metabolism, thereby reducing metabolism. Different surgical and radio-oncological therapeutic options are available based on different stages of this disease. A pre-S vaccine (Sci-B-Vac) has demonstrated superior immunogenicity compared with standard HBV vaccines in several diseases.

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These vagal afferent nerves may interact centrally with sensory input arising from afferent nerves innervating the intrapulmonary airways or even extrapulmonary afferents such as those innervating the nasal mucosa and esophagus to produce chronic cough or enhanced cough responsiveness. The occlusion was performed in the basilar, the anterior cerebellar and in the internal auditory arteries. Yenepoya University Ethics Committee, India has approved the study protocol (YUEC/148/2016 on 18 February 2016). Observational, prospective and multicenter study based on a wide source of data incoming from 50 Intensive Care Units in Spain during 15 years, from April 1996 to December 2010. This study provides the first evidence for a procoagulant other than TF that is associated with leukemic cells.

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The fibromyalgia symptoms may relate to a non-restorative sleep disorder associated with the alpha-EEG sleep anomalies. We evaluated CO2 elimination by low frequency IPPV under thoracotomy through observation of both PaCO2 and PetCO2. These findings show that ovarian epithelial cells contain different glycoconjugates and that malignant transformation is accompanied by changes in the composition of these glycoconjugates. A rotating drum stimulator for scanning embossed patterns and textures across the skin. A report of solid- to liquid-state DNP of a short peptide, bacitracin A, as well as of a full-length protein, L23, is presented here.

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A reliable method for epicardial atrial and atrioventricular pacing: the loop electrode. Alpha2-macroglobulin in various pathological conditions of the prostate Using exposure modeling of saxagliptin and its active metabolite, 5-hydroxy saxagliptin, as an example, this work illustrates how these challenges can be alleviated by modeling the impact of HD on drug exposure in clinical studies and simulating the expected exposure level in patient care. All patients experienced significant improvement in handicap and they all maintained community placements.

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Experience with metoclopramide therapy in early pregnancy toxicosis Noncorrelating Pap tests and cervical biopsies: histological predictors of subsequent correlation. The effect of NMDA was the same throughout the culture period and was dependent upon the concentration of extracellular calcium with no effect at 2 mM and maximal effect at 4 mM calcium. Enhancement of succinate production by metabolically engineered Escherichia coli with co-expression of nicotinic acid phosphoribosyltransferase and pyruvate carboxylase. The tensile bond strengths of a resin cement, Panavia Ex, to a spherical and an admixed amalgam were measured after surface treatment with different aluminum oxide abrasive spray procedures.

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An immunotherapy schedule in endocrine-dependent metastatic breast cancer: correlation between clinical course and immunologic parameters. Therefore, we concluded that the patient had a hypersensitivity reaction similar to sarcoidosis. A principal component analysis (PCA) of (1)H-NMR data from the guava leaves provided clear clusters according to the harvesting time.

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aureus isolate, (2) a hyperimmune rabbit serum raised against an isolate of S. Pulsed electric field (PEF) treatment has been successful as a nonthermal microbial inactivation-pasteurization method within the food industry. We have now studied the question of whether in vitro resistance selection (IVRS) with RAL initiated with viruses derived from clinical isolates would result in selection of resistance mutations consistent with those arising during treatment regimens with HAART containing RAL.

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In the rat testis, restructuring of the blood-testis barrier (BTB) formed between Sertoli cells near the basement membrane and disruption of the apical ectoplasmic specialization (apical ES) between Sertoli cells and fully developed spermatids (spermatozoa) at the luminal edge of the seminiferous epithelium occur concurrently at stage VIII of the seminiferous epithelial cycle of spermatogenesis. The in vitro translation products of two different human isolates of Giardia lamblia, WB 2x and GS/E, were compared in order to determine common protein constituents and to identify proteins recognized by the infected host. Recent epidemiologic studies have identified a high frequency of oversedation in the ICU that is attributable, in part, to a number of pharmacokinetic, pharmacogenetic, and pharmacodynamic factors. Recently, ensemble learning methods have been widely used to improve classification performance in machine learning.

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Calcium current is increased in isolated adult myocytes from hypertrophied rat myocardium. Nanoscale fluctuations of the In content in the InGaN layer of a few percent can be identified and visualized with a lateral resolution below 35 nm. The cost-effectiveness ratios were low, indicating good economic value in the adjuvant setting of node-positive breast cancer patients. N-myc amplification and neuron-specific enolase production of a neuroblastoma cell line and germ cell tumor cell lines.

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This suggested that the increase in hydrophobic carbon chain in LC-SPDP-oLH molecules resulted into the drastic inhibition in the immunological and biological properties. In this report, four cell cycle compartments (A-D) are defined by characteristic ratios of red and green fluorescence of cells distributed throughout the erythrocytic cycle as well as by the differential effects of several metabolic inhibitors. Alcoholics Anonymous-Related Helping and the Helper Therapy Principle.

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Atypical cases of Pityriasis rosea are fairly common and less readily recognized than typical eruptions, and may pose a diagnostic challenge. Map-based cloning revealed that the rice flowering-time quantitative trait locus (QTL) Heading date 16 (Hd16) encodes a casein kinase-I protein. Silicone hydrogel contact lenses contaminated with a human CLARE isolate of Pseudomonas aeruginosa at inocula ranging from 1 x 10 to 6 x 10 colony-forming units (CFUs) for 15 minutes, 1 hour, or 24 hours were worn by guinea pigs for times up to 48 hours in 3 models designed to simulate contamination during wear and contact lens care regimens. SP pneumonia generally remains associated with substantial mortality while azithromycin treatment is associated with significantly higher survival rates. However, their use in esophageal reconstruction has become limited and has been largely replaced by other techniques as a result of the popularity of combined therapy programs utilizing radiation therapy, which decreases the viability of cervical tissue used in such reconstruction.

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It is one of the most elaborate subcellular protein structures in eukaryotes, comprising more than 100 different proteins. Pulmonary mucormycosis mimicking as pulmonary tuberculosis: a case report. The drug encapsulated in immunoliposomes inactivated the virus and exhibited more chemotherapeutic efficacy as compared to controls when injected up to 24 h post-infection. During the past decade, a number of genes have been reported to cause JALS.

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The level of neopterin in blood serum in premature newborn in the process of their adaptation to postnatal life Recent authors have pioneered the use of single-incision laparoscopic surgery (SILS) for umbilical cholecystectomy.

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These results demonstrate parallels in differentiation between trichomes in cotton and Arabidopsis, and indicate that these cotton genes may be functional homologues of AtTTG1. The RCN and Nursing Standard this week jointly launched a major national campaign to highlight the threats to patient services caused by cuts in nursing posts.

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Although the primary patency rates were not colossal, excellent secondary and cumulative patency rates were observed for SAVF in this study. Chronic experimental diabetes accelerates urinary elimination of deprenyl and its metabolites. to oral may be done even on the first day of infection if the patient is not in shock and able to take oral medication. In this study, proprioceptive contributions to lateral trunk motion were examined during paraspinal muscle vibration. CT Scan was considered as the first line investigation modality.

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Metformin was found to provide adequate glycemic control with lower mean glucose levels throughout the day, less weight gain and a lower frequency of neonatal hypoglycemia. Immunohistochemically, PTA was demonstrated to be localized within the cytoplasm of epithelial tumor cells of well-differentiated tubular adenocarcinomas. The involvement of a systemic inflammatory response, as evidenced by the Glasgow Prognostic Score (GPS), is associated with weight loss and poor outcome in patients with non-small cell lung cancer.

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The abnormality was most profound if the noun denoting the object could not be recognized. Effect of propylthiouracil on liver cell development in the male albino mouse: protective effect against ethanol-induced alterations. The vascular complications of herpes zoster are well recognised, however, there are few reports of central retinal artery occlusion.

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Its effects can impair the efficacy of opioids used for postoperative pain. We also investigated the relationship between iris abnormalities and other phenotypical features of albinism. Effect of bar cross-section geometry on stress distribution in overdenture-retaining system simulating horizontal misfit and bone loss.

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The aim of this study was to examine knowledge, perceived risk, feelings of anxiety, and behavioral responses of the general public in relation to tick bites and LD in the Netherlands. Myocardial uptake of (99m)Tc-DPD scintigraphy was semiquantitatively and visually assessed at 5 min and 3 h. Urinary beta 2-microglobulin as an indicator of proximal renal tubular dysfunction in asphyxiated full-term newborns. Secretory processes and deposition of the cuticle start in the larva, immediately after transformation. Systemic embolization is a rare but serious complication of variceal injection with cyanoacrylate.

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These data suggest that platelets play some role in the response to paracentesis, a fact in accordance with histological results. Constant antimicrobial surveillance is warranted to observe for the emergence of enteric bacteria resistant to antimicrobials that are important in treatment also of severe infections. Patients also may exhibit an isolated cone dystrophy on ERG examination.

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The spindle checkpoint delays sister chromatid separation until all chromosomes have undergone bipolar spindle attachment. Indices for the clinical evaluation of drug gingival hyperplasia using the example of cyclosporin A The role of MCM proteins in cell proliferation and tumorigenesis Many phenolic, dihydroxylated, and methoxylated aromatic acids, as well as aromatic aldehydes and hydroaromatic acids, supported growth of strain CGA001 in both the presence and absence of oxygen. Particularly for internal exposures, we show that such standards may correspond poorly with a limit on lifetime risk when the age dependence of radionuclide intakes and dose is taken into account.

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In rat salivary activity, gastric secretion and rabbit gastric-motility, the anticholinergic activities of parenterally administered Ba 253 were 2.3 to 11.8 times and 1 to 2 times stronger than that of atropine and Sch 1000, respectively. Nitric oxide (NO), produced by nitric oxide synthase (NOS), critically counteracts angiotensin-II-enhanced vascular resistance in the immature kidney, perhaps due to the developmental regulation of NOS expression and function in the postnatal preglomerular resistance vessels (PRV). Osthole decreases renal ischemia-reperfusion injury by suppressing JAK2/STAT3 signaling activation. This study was to explore application of combined therapy of intraoperative hypotonic peritoneal chemo-hyperthermia and early postoperative intraperitoneal chemotherapy to gastric cancer. These results suggest that NQO1 is a positive regulator of the pigmentation process.

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The relationship between distress tolerance and antisocial personality disorder among male inner-city treatment seeking substance users. Expression levels of BIRC5, TK1, TNNT1 and MMP9 were found to be positively related to postoperative relapse.

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The effects of obesity on the respiratory system have received less attention and are the subject of this article. Melatonin reduces tissue destruction during inflammatory reactions by a number of means. MR features of primary and secondary malignant lymphoma of the pancreas: a pictorial review.

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A comparison of the spontaneous occurrence of arrhythmias with ventricular inhibited pacing was also made. Whether the beneficial effect induced by capsaicin application to the nasal mucosa could be ascribed to a specific action on sensory neurons remains unknown.

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The goal of the present study was to assess the prevalence of psychosocial distress and the extent of contact between the PCT and distressed patients. In this retrospective study, the case records of patients with vitiligo during the period from January 2006 to December 2010 were studied. We aimed to determine the prevalence of MTB multiple strain infections in Kampala, and the impact of these infections on clinical presentation of tuberculosis (TB) and response to treatment. Obesity and associated metabolic diseases are sexually dimorphic. Self-cementing properties of oil shale solid heat carrier retorting residue.

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The total cell and neutrophil counts in BALF were increased from day 3 to 3 months. We especially attached importance on the complete registration of all inhabitants to get a reliable sample for regional comparison of morphological features. We therefore investigated the relationship between disease distribution and the population genetic structure of the black rat, Rattus rattus, the main reservoir of plague in Madagascar.

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The implications of this global phenomenon on future generations will be serious unless appropriate action is taken. Immunity is expressed in heightened resistance to mucosal invasion by L1 larvae, and the change in structure is evident in reduced membrane binding of the lectin, wheat germ agglutinin.

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In the rest of the epithelium, injury amplified membrane infolding and fluorescence of polygonal arrays but diminished the size and fluorescence intensity of SABs. No significant associations are found between inattentive symptoms and sleep quality. Each session consisted of three maximum voluntary bites at three bite positions (incisor and right and left molars). The postreatment data suggested that there were no significant changes in the vertical skeletal parameters.

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Regulatory mechanisms of young men heart rate during psychoemotional load accompanied by irritation with different sounds Study of a preparation for external use with a rifamycin SV base Most patients from the surgery departments completed the questionnaires voluntarily and anonymously. This procedure has been packaged into an NMR-assisted prediction of secondary structure (NAPSS) algorithm that can produce pseudoknotted as well as non-pseudoknotted secondary structures. Noninfectious RV-like particles (VLPs) containing three structural proteins were expressed in a BHK cell line (BHK-24S) by using an inducible promoter.

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Specific inhibition of tyrosine kinase activity by an antibody to the v-ros oncogene product. Mechanisms of chronic nicotine treatment-induced enhancement of the sensitivity of cortical neurons to the neuroprotective effect of donepezil in cortical neurons.

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This study aimed to identify whether these biochemical markers can be used to identify if patients are suitable for either a conservative or surgical approach. Digital archives and communication highways in health care require a second look at the legal framework of the seventies. Our work uncovers roles for Cohibin complexes and reveals relationships between nuclear compartmentalization, chromosome stability, and aging. Effects of membrane cholesterol depletion and GPI-anchored protein reduction on osteoblastic mechanotransduction. Extracorporeal shockwave lithotripsy in the treatment of urolithiasis--experiences from a center with the Piezolith 2200 and HM3 lithotriptors